Study and analyze the correlation between the prognosis of pulmonary surfactant protein A and community-acquired pneumonia

Objective to discuss the correlation between the prognosis of pulmonary surfactant protein A (SP-A) and community-acquired pneumonia (CAP). Methods 100 CAP patients, from August 2013 to September 2014, were selected randomly. According CURB-65 evaluative criteria, patients were divided into mild group, moderate group and severe group respectively; In accordance with the criteria of CAP critical rating 7, patients were divided into low, intermediate, high and extremely high risk groups. The differences on the clinical prognostic indicators (hospital stays, mechanical ventilation and oxygenation index) through comparisons among groups. Results SP-A content and oxygenation index for patients between moderate and severe groups were significantly less than those in mild group (P < 0.05), while the hospital stays and mechanical ventilation were distinctly larger than those in mild group (P < 0.05). The SP-A content and oxygenation index of patients among intermediate, high and extremely high risk groups were significantly less than those in low-risk group (P < 0.05), while the hospital stays and mechanical ventilation were remarkably larger than those in low-risk group (P < 0.05). Conclusion SP-A, a sensitive and accurate biological specific indicator, shows a crucial evaluation value on the disease severity and prognosis of CAP.