DO (Dissolved Oxygen) and BOD (Biochemical Oxygen Demand) are indicators capable of representing how much pollution occurs due to the ingress of organic matters into water bodies. Domestic wastes, agricultural wastes, and livestock wastes are sources of organic pollutants. This study aims to determine the dynamics of DO-BOD concentrations in Madiun river caused by organic waste originating from domestic household waste due to population activity associated with the total population, the total area of agricultural land and the number of community livestock in the watershed. The methods used were direct observation and analysis of secondary data from the related institutions. These data were analyzed using a descriptive method. The results show the lowest DO concentrations was 4.5 mg/L, the highest was 6.1 mg/L and the lowest BOD concentrations was 2.0 mg/L, the highest was 14.7 in the year 2015. The lowest DO concentrations was 3.1 mg/L, the highest was 8.0 mg/L and the lowest was BOD concentrations was 4.9 mg/L, the highest was 13.7 in the year 2016. The lowest DO concentrations was 4.7 mg/L, the highest was 8.36 mg/L and the lowest BOD was 3.7 mg/L, the highest was 9.52 in the year 2017. The factors that affect the dynamics of DO-BOD concentrations are total populations, the number of paddy fields, the number of livestock and rainfall.

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