Porcupine Bezoar Extract (PBE) has been previously described to possess diverse medicinal properties. In any case, its potential and ability as anti-cancer agent on HeLa cell line are still poorly studied and understood. Hence, in this research, Porcupine Bezoar Extract (PBE) aqueous extract was figure out for its potential as a safe anti-cancer agent. Initially, Porcupine Bezoar Extract (PBE) was infused with distilled water for 18 hours to get PBE aqueous solution in order to confirm the presence of bioactive agents as antioxidants. Later, PBE aqueous solution was subjected to HeLa cell line and was observed for 48 hours exposures with comparative to the untreated cell to evaluate its anticancer potential and ability. The data from this study propose the potential agents for improving human health, especially in the anti-cancer application.
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29 November 2018
3RD INTERNATIONAL SCIENCES, TECHNOLOGY & ENGINEERING CONFERENCE (ISTEC) 2018 - MATERIAL CHEMISTRY
17–18 April 2018
Penang, Malaysia
Research Article|
November 29 2018
In-vitro evaluation of porcupine bezoar extracts (PBE) as anti-cancer agent on HeLa cell line – A preliminary study Free
Azra Hazwanie Azizulkarim;
Azra Hazwanie Azizulkarim
1
Biomedical Modelling and Simulation (BIOMEMS) Research Group, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia
, 86400 Batu Pahat, Johor, Malaysia
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Muhammad Mahadi Abdul Jamil;
Muhammad Mahadi Abdul Jamil
a)
1
Biomedical Modelling and Simulation (BIOMEMS) Research Group, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia
, 86400 Batu Pahat, Johor, Malaysia
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Mohamad Nazib Adon;
Mohamad Nazib Adon
1
Biomedical Modelling and Simulation (BIOMEMS) Research Group, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia
, 86400 Batu Pahat, Johor, Malaysia
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Ridhwan Abdul Wahab;
Ridhwan Abdul Wahab
2
Department of Biomedical Science, Kulliyah of Allied Health Sciences University Malaysia
, 25200 Kuantan, Pahang, Malaysia
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Tengku Nadzlin Tengku Ibrahim;
Tengku Nadzlin Tengku Ibrahim
1
Biomedical Modelling and Simulation (BIOMEMS) Research Group, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia
, 86400 Batu Pahat, Johor, Malaysia
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Salehhuddin Hamdan;
Salehhuddin Hamdan
3
Department of Biosciences and Health Sciences, Universiti Teknologi Malaysia
, 81310 UTM Johor Bahru, Johor, Malaysia
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Sayang Baba
Sayang Baba
3
Department of Biosciences and Health Sciences, Universiti Teknologi Malaysia
, 81310 UTM Johor Bahru, Johor, Malaysia
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Azra Hazwanie Azizulkarim
1
Muhammad Mahadi Abdul Jamil
1,a)
Mohamad Nazib Adon
1
Ridhwan Abdul Wahab
2
Tengku Nadzlin Tengku Ibrahim
1
Salehhuddin Hamdan
3
Sayang Baba
3
1
Biomedical Modelling and Simulation (BIOMEMS) Research Group, Faculty of Electric and Electronic Engineering, Universiti Tun Hussein Onn Malaysia
, 86400 Batu Pahat, Johor, Malaysia
2
Department of Biomedical Science, Kulliyah of Allied Health Sciences University Malaysia
, 25200 Kuantan, Pahang, Malaysia
3
Department of Biosciences and Health Sciences, Universiti Teknologi Malaysia
, 81310 UTM Johor Bahru, Johor, Malaysia
AIP Conf. Proc. 2031, 020024 (2018)
Citation
Azra Hazwanie Azizulkarim, Muhammad Mahadi Abdul Jamil, Mohamad Nazib Adon, Ridhwan Abdul Wahab, Tengku Nadzlin Tengku Ibrahim, Salehhuddin Hamdan, Sayang Baba; In-vitro evaluation of porcupine bezoar extracts (PBE) as anti-cancer agent on HeLa cell line – A preliminary study. AIP Conf. Proc. 29 November 2018; 2031 (1): 020024. https://doi.org/10.1063/1.5066980
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