The study aimed to explore potential antioxidant effects of organic taurine and oyster mushroom (Pleurotus ostreatus (Jacq.) P. Kumm) on diets of male mice induced by paraquat herbicide. Thirty male mice were assigned for this study. They were divided into five groups, namely control, oyster mushroom diet, paraquat, paraquat plus oyster mushroom diet, and paraquat plus taurine diet. The concentration of malondialdehyde (MDA), Glutathione, and superoxide dismutase (SOD) was measured, after three weeks animals were intraperitoneally given paraquat twice a week as much as 20 mg · kg−1 BW. Taurine was given 15.6 g · kg−1 BW and the oyster mushroom pellet was given 62.5 g · kg−1 daily. Complete randomized design was applied to these groups and data was analyzed using ANOVA followed by LSD at 5 %. The results indicated that both additions of taurine and oyster mushroom on diets reduced the concentration of MDA for about 15 % and increased the glutathione concentration for about 30 % (p < 0.05), while the concentration of SOD did not show any significantly different among groups (p > 0.05), even though both taurine and oyster mushroom diets decreased SOD concentration for about 12 %. In conclusion, both taurine and oyster mushroom affected as an antioxidant by reducing the MDA concentration and increasing in glutathione concentration.
Skip Nav Destination
Article navigation
15 August 2018
INVENTING PROSPEROUS FUTURE THROUGH BIOLOGICAL RESEARCH AND TROPICAL BIODIVERSITY MANAGEMENT: Proceedings of the 5th International Conference on Biological Science
15–16 September 2017
Yogyakarta, Indonesia
Research Article|
August 15 2018
Antioxidant role of taurine and oyster mushroom on kidneys of male mice induced by paraquat herbicide
Endang Linirin Widiastuti;
Endang Linirin Widiastuti
a)
1
Department of Biology, Faculty of Mathematics and Science, University of Lampung
, Lampung, Indonesia
aCorresponding author: endang.linirin@fmipa.unila.ac.id
Search for other works by this author on:
Endang Nurcahyani;
Endang Nurcahyani
1
Department of Biology, Faculty of Mathematics and Science, University of Lampung
, Lampung, Indonesia
Search for other works by this author on:
Bayu Putra Danan Jaya
Bayu Putra Danan Jaya
2
Faculty of Medical Science, University of Lampung
, Lampung, Indonesia
Search for other works by this author on:
aCorresponding author: endang.linirin@fmipa.unila.ac.id
AIP Conf. Proc. 2002, 020021 (2018)
Citation
Endang Linirin Widiastuti, Endang Nurcahyani, Bayu Putra Danan Jaya; Antioxidant role of taurine and oyster mushroom on kidneys of male mice induced by paraquat herbicide. AIP Conf. Proc. 15 August 2018; 2002 (1): 020021. https://doi.org/10.1063/1.5050117
Download citation file:
Citing articles via
Related Content
Contamination of paraquat residues in soil and water from several provinces in Indonesia
AIP Conference Proceedings (July 2019)
Removal of paraquat solution onto zeolite material
AIP Conference Proceedings (April 2018)
Point-of-care testing in the early diagnosis of acute pesticide intoxication: The example of paraquat
Biomicrofluidics (January 2018)
Effects of taurine and ethanol extract from Sargassum sp. to cervical cancer cells (HeLa) in vitro
AIP Conference Proceedings (October 2022)
Paper-based diagnostic devices for clinical paraquat poisoning diagnosis
Biomicrofluidics (June 2016)