To observe the effect of Guci Powder on foot swelling induced by egg white in rats. 50 male rats were randomly divided into normal saline group (n=10), white vinegar group (n=10) and Guning lotion group (n=10). There were 10 rats in the high-dose group and 10 in the low-dose group. The rats in each group were treated with the drug on the left and right feet of the rats. 0.5 hours after the last administration, the rats in each group were inflamed. The left hindsole plantar volume was measured respectively, so that the difference of the posterior toe volume before inflammation was taken as the swelling degree, and the swelling degree of each group was calculated. Compared with physiological saline group, the rats’ egg white toe swelling (P<0.01) was significantly inhibited at 0.5∼6h after administration. The swelling of egg white toe in rats was inhibited at 0.5∼2h (P<0.05). Bone spur powder has a good intervention effect on the model of toe swelling induced by egg white in rats, and the external application of bone spur powder has anti-inflammatory and swelling effect.

Topics
Inflammation, Anti-inflammatory
1.
G.Q.
 
Xie
,
X.D.
 
Wang
,
Z.Z.
 
Ma
,
Chin. Med. Evaluation & Analysis
,
16
,
155
(
2016
)
Google Scholar
 
2.
Z.Z.
 
Ma
,
W.J.
 
Li
,
G.Q.
 
Xie
,
Chin. Med. Evaluation & Analysis
,
16
,
245
(
2016
)
Google Scholar
 
3.
S.Y.
 
Li
,
Q.F.
 
Bu
,
F.
 
Su
,
Chin. Med. Infor.
,
20
,
41
(
2003
)
Google Scholar
 
4.
H.Q.
 
Hao
,
Y.F.
 
Wang
,
Chin. Fact. Min. Med.
,
3
,
192
–
193
(
1997
)
Google Scholar
 
5.
S.L.
 
Liang
,
Q.
 
Liang
,
W.H.
 
Zhong
,
Chin. Herbs
,
45
,
3131
–
3135
(
2014
)
Google Scholar
 
6.
H.D.
 
Lv
,
F.H.
 
Zhang
,
Z.Z.
 
Ma
,
Hebei Med.
,
35
,
1937
–
1938
(
2013
)
Google Scholar
 
7.
M.
 
Chen
,
Y.
 
Li
,
M.S.
 
Miao
,
J. Traditional Chin. Med.
,
31
,
1142
–
1144
(
2016
)
Google Scholar
 
8.
S.Y.
 
Xu
,
R.L.
 
Bian
,
X.
 
Chen
,
Pharmacology Experiment Methodology M. 2 edition
(
People’s Medical Publishing House
,
Beijing
,
1991
)
Google Scholar
 
9.
Y.
 
Tian
,
Med. Infor.
,
28
,
371
(
2015
)
Google Scholar
 
10.
Z.Y.
 
Tang
,
S.L.
 
Wang
,
Y.
 
Lin
,
Chin. J. Clinical Phar.
,
26
,
535
–
539
(
2010
)
Google Scholar
 
11.
S.L.
 
Zhu
,
P.F.
 
Huang
,
Y.F.
 
Wang
,
Strait Phar. J.
,
19
,
9
–
11
(
2007
)
Google Scholar
 
12.
P.
 
Guo
,
G.
 
Liang
,
S.L.
 
Yang
,
China Med.
,
11
,
768
–
772
(
2016
).
Google Scholar
 
13.
Z.Y.
 
Wang
,
H.
 
Ren
,
H.M.
 
Wang
,
Proceed. Clinical Med.
,
21
,
494
–
497
(
2012
)
Google Scholar
 
14.
M.B.
 
Li
,
Q.
 
Yang
,
X.Y.
 
Chen
,
China Med. Phar.
,
1
,
121
–
122
(
2011
)
Google Scholar
 
15.
Y.Q.
 
Zhao
,
L.X.
 
Yang
,
X.M.
 
Zhang
,
M.H.
 
Qiu
,
J. Chin. Med. Mater.
,
31
,
465
(
2008
)
Google Scholar
 
16.
R.
 
Hu
,
B.G.
 
Le
,
J. Med. Phar. Chin. Minorities
,
2
,
68
–
69
(
2009
)
Google Scholar
 
This content is only available via PDF.
© 2018 Author(s).
2018
Author(s)