To investigate the effect of Qing Nao tablet on mouse model of blood stasis syndrome, 60 mice, male and female, were randomly divided into 6 groups, were fed with large, small doses of Qing Nao tablet suspension, Naoluotong saline suspension and the same volume (group 2, 0.1ml/10g), administer 1 times daily, orally for 15 days. Intragastric administration for first days, in addition to the 1 group saline group every day in the hind leg intramuscular saline, the other 5 groups each rat day hind leg muscle injection of dexamethasone 0.8mg/kg intramuscular injection every day, 1 times, 15 days. 1 hour continuous intramuscular injection and intramuscular drug perfusion on the sixteenth day after mice. The eyeball blood, heparin after whole blood viscosity test. Compared with the control group, model group, high and low shear viscosity were significantly increased (P<0.01), indicating that the model was successful. Compared with the model group, high dose group and Qing Nao tablet Naoluotong group can significantly reduce the viscosity at high shear and (P<0.01), middle dose Qing Nao tablet group can significantly reduce high shear and shear viscosity (P<0.05); large, middle dose Qing Nao tablet group can significantly reduce the low shear viscosity (P<0.05), Naoluotong group can significantly reduce the low shear viscosity (P<0.01); low dose Qing Nao tablet group were lower high cut, low shear viscosity and trend The potential (P>0.05). The Qing Nao tablet has a good effect on the model of blood stasis in mice.
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27 April 2018
2017 INTERNATIONAL CONFERENCE ON BIOTECHNOLOGY AND BIOENGINEERING (ICBB-2017)
26–28 September 2017
Offenburg, Germany
Research Article|
April 27 2018
Effect of Qing Nao tablet on blood stasis model of mice
Xuejun Kong;
Xuejun Kong
1
The 371st Central Hospital of PLA
, Xinxiang, 453000 China
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Shaojun Hao;
Shaojun Hao
1
The 371st Central Hospital of PLA
, Xinxiang, 453000 China
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Hongyu Wang;
Hongyu Wang
a)
1
The 371st Central Hospital of PLA
, Xinxiang, 453000 China
a)Corresponding author: [email protected]
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Xiaobin Liu;
Xiaobin Liu
1
The 371st Central Hospital of PLA
, Xinxiang, 453000 China
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Guoqi Xie;
Guoqi Xie
1
The 371st Central Hospital of PLA
, Xinxiang, 453000 China
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Wenjun Li;
Wenjun Li
1
The 371st Central Hospital of PLA
, Xinxiang, 453000 China
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Zhengchen Zhang
Zhengchen Zhang
1
The 371st Central Hospital of PLA
, Xinxiang, 453000 China
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a)Corresponding author: [email protected]
AIP Conf. Proc. 1956, 020040 (2018)
Citation
Xuejun Kong, Shaojun Hao, Hongyu Wang, Xiaobin Liu, Guoqi Xie, Wenjun Li, Zhengchen Zhang; Effect of Qing Nao tablet on blood stasis model of mice. AIP Conf. Proc. 27 April 2018; 1956 (1): 020040. https://doi.org/10.1063/1.5034292
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