To investigate the effect of anti-glare particles on sedation of mice, 60 mice were randomly divided into 5 groups, were fed by Ant-dizzy Granule Suspension, saline, Yang Xue Qing Nao Granule suspension and the same volume of saline, and administered 1 times daily, for 7 days. The mice in the wilderness box, hang - 150W light bulbs in the box above, the light recording activities within 2 minutes. The wilderness box into the box after the number of mice, mice with limbs went to the 1 squares is around 1 in the same case, mouse location and method of wilderness case; each group was placed in the turn/bar with rotating speed of 40RPM, each time 5 Parallel experiment recorded the mouse stay time on the rotating rod, if the mouse fell within 2 minutes, immediately put it on the rotating rod to continue the experiment, recorded the mouse on the rotating rod accumulated stay time. If 10 minutes did not drop, press 10 minutes; eighty mice were divided into 5 groups. The number of each rat injected subthreshold dose of pentobarbital sodium in mice. The sleep recording liquid were recorded sleep latency and sleep time. The anti-vertigo granule can obviously reduce the spontaneous activity of mice (P<0.05), can significantly increase the residence time of mice on the rotating rod (P<0.05) have obvious synergistic effect (P<0.05). Anti-glare particles have good sedative effect.
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27 April 2018
2017 INTERNATIONAL CONFERENCE ON BIOTECHNOLOGY AND BIOENGINEERING (ICBB-2017)
26–28 September 2017
Offenburg, Germany
Research Article|
April 27 2018
Effects of anti-glare particles on sedation in mice
Hongyu Wang;
Hongyu Wang
Chinese people’s Liberation Army 371st Center Hospital
, Xinxiang 453000, China
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Shaojun Hao;
Shaojun Hao
Chinese people’s Liberation Army 371st Center Hospital
, Xinxiang 453000, China
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Xiaobin Liu;
Xiaobin Liu
Chinese people’s Liberation Army 371st Center Hospital
, Xinxiang 453000, China
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Xuejun Kong;
Xuejun Kong
a)
Chinese people’s Liberation Army 371st Center Hospital
, Xinxiang 453000, China
a)Corresponding author: [email protected]
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Xidong Wang;
Xidong Wang
Chinese people’s Liberation Army 371st Center Hospital
, Xinxiang 453000, China
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Wenjun Li;
Wenjun Li
Chinese people’s Liberation Army 371st Center Hospital
, Xinxiang 453000, China
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Zhengchen Zhang
Zhengchen Zhang
Chinese people’s Liberation Army 371st Center Hospital
, Xinxiang 453000, China
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a)Corresponding author: [email protected]
AIP Conf. Proc. 1956, 020036 (2018)
Citation
Hongyu Wang, Shaojun Hao, Xiaobin Liu, Xuejun Kong, Xidong Wang, Wenjun Li, Zhengchen Zhang; Effects of anti-glare particles on sedation in mice. AIP Conf. Proc. 27 April 2018; 1956 (1): 020036. https://doi.org/10.1063/1.5034288
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