This study aimed to determine the antibacterial activity of β-Glucan (laminaran) of LAE and LME extracts from brown algae Sargassum crassifolium using HPMS and Ultrasonication against Gram-positive bacteria (Bacillus subtilis and Staphylococcus aureus) and Gram-negative bacteria (Salmonella typhimurium and Escherichia coli). The highest antibacterial activities of LME extract obtained using the HPMS method against Gram-positive bacteria (B. subtilis and S. aureus) were at 18:10 and 18.80 mm. The ultrasonication method showed a lower inhibition trend than the HPMS method, with MIC and MBC values of 250 mg/ml and 2-8 CFU/ml, respectively, in all Gram-negative and Gram-positive bacteria. The results showed that LME extract at a concentration of 250 mg/mL is bacteriostatic against Gram-positive and –negative bacteria.
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Research Article| May 17 2017
Antibacterial activities of β-glucan (laminaran) against gram-negative and gram-positive bacteria
AIP Conf. Proc. 1844, 020011 (2017)
A. Chamidah, Hardoko, A. A. Prihanto; Antibacterial activities of β-glucan (laminaran) against gram-negative and gram-positive bacteria. AIP Conf. Proc. 17 May 2017; 1844 (1): 020011. https://doi.org/10.1063/1.4983422
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