Stem length and cross section are two key parameters that influence the stability and longevity of metallic hip prosthesis in the total hip arthroplasty (THA). In order to assess their influence to the stress and fatigue behavior of hip prosthesis, a series model of hip prosthesis with round‐shaped or drum‐shaped cross section, and with different stem lengths were created. These models were analyzed under both static and dynamic loading conditions with finite element analysis, and dynamic loading represents normal walking was used in the dynamic analysis. The stress on the metallic stem, cement, and adjacent bone were got, micromotion on the cement‐metal interface were got too. Safety factors for fatigue life of the hip prothesis were calculated based on data obtained from dynamic analysis. Static analysis shows that drum‐shaped cross section can decrease the displacement of the stem, that stress on drum‐shaped stem focus on the corner of the femoral neck and the distal part of hip prosthesis, whereas the stress on the round‐shaped stem distributes evenly over most part of the stem, and maximum stress on stem prosthesis fluctuates with stem length bottoming out at stem length range from 80 mm to 110 mm, that drum‐shaped stems with drum height 8 mm generate more stress at the distal part of stem than drum‐shaped stems with drum height 10 mm and round stems do. Dynamic and fatigue analysis shows that drum‐shaped stem with drum height 10 mm and stem length 90 mm has the greatest safety factor therefore long fatigue life.

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