In the study carried out in goats, we used the JC200 focused ultrasound tumor therapeutic system (Chongqing Haifu Tech Co., Ltd, China). The therapeutic ultrasound energy is produced by a transducer with a focal length of 160mm, at a frequency of 0.8MHz. The animals (n=6) were divided into a control group (n=3) and an experimental group subjected to costectomy (n=3). Costectomy was performed 1 week before HIFU. There was no difference in the coagulation volume between the two groups. Skin burns accompanied with reddish color and focal edema were observed in two goats. There were no other complications. In the clinical study, HIFU was applied in patients with with ⩽ 3 lesions of liver carcinoma ⩽ 4cm in diameter. The complications and anti‐tumor effects on liver carcinomas should be evaluated. Tumor ablation was complete in 5 of 6 patients. There were no complications such as skin burns and local pain. HIFU did not influence blood chemical findings.
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21 May 2007
6TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND
30 August-2 September 2006
Oxford (United Kingdom)
Research Article|
May 21 2007
Animal and Clinical Studies for the Treatment of Liver Carcinomas with High‐Intensity Focused Ultrasound (HIFU) Available to Purchase
Hiroyuki Fukuda;
Hiroyuki Fukuda
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Taketo Yamaguchi;
Taketo Yamaguchi
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Seigo Yukisawa;
Seigo Yukisawa
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Yoshio Masuya;
Yoshio Masuya
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Kentaro Sudo;
Kentaro Sudo
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Shinichiro Okabe;
Shinichiro Okabe
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Masaharu Yoshikawa;
Masaharu Yoshikawa
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Masaaki Ebara;
Masaaki Ebara
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Hiromitsu Saisho;
Hiromitsu Saisho
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Masao Ohto;
Masao Ohto
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Norihiro Shinozuka;
Norihiro Shinozuka
†Department of Anesthesiology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
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Fagi Li;
Fagi Li
‡Institute of Ultrasonic Engineering in Medicine, Chongqing University of Medical Sciences, Chongqing, China
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Hui Zhu;
Hui Zhu
¶Clinical Center of Tumor Therapy of 2nd Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, China
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Chengbin Jin;
Chengbin Jin
¶Clinical Center of Tumor Therapy of 2nd Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, China
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Feng Wu;
Feng Wu
¶Clinical Center of Tumor Therapy of 2nd Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, China
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Zhi‐Biao Wang
Zhi‐Biao Wang
‡Institute of Ultrasonic Engineering in Medicine, Chongqing University of Medical Sciences, Chongqing, China
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Hiroyuki Fukuda
st
Taketo Yamaguchi
st
Seigo Yukisawa
st
Yoshio Masuya
st
Kentaro Sudo
st
Shinichiro Okabe
st
Masaharu Yoshikawa
st
Masaaki Ebara
st
Hiromitsu Saisho
st
Masao Ohto
st
Norihiro Shinozuka
gger
Fagi Li
ggers
Hui Zhu
ra
Chengbin Jin
ra
Feng Wu
ra
Zhi‐Biao Wang
ggers
*Department of Medicine and Clinical Oncology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
†Department of Anesthesiology, Graduate School of Medicine, Chiba University, Inohana 1‐8‐1, Chuo‐ku, Chiba‐shi, Chiba 260‐0856, Japan
‡Institute of Ultrasonic Engineering in Medicine, Chongqing University of Medical Sciences, Chongqing, China
¶Clinical Center of Tumor Therapy of 2nd Affiliated Hospital, Chongqing University of Medical Sciences, Chongqing, China
AIP Conf. Proc. 911, 375–381 (2007)
Citation
Hiroyuki Fukuda, Taketo Yamaguchi, Seigo Yukisawa, Yoshio Masuya, Kentaro Sudo, Shinichiro Okabe, Masaharu Yoshikawa, Masaaki Ebara, Hiromitsu Saisho, Masao Ohto, Norihiro Shinozuka, Fagi Li, Hui Zhu, Chengbin Jin, Feng Wu, Zhi‐Biao Wang; Animal and Clinical Studies for the Treatment of Liver Carcinomas with High‐Intensity Focused Ultrasound (HIFU). AIP Conf. Proc. 21 May 2007; 911 (1): 375–381. https://doi.org/10.1063/1.2744300
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