We present a novel technique for synchronizing diagnostic ultrasound imaging and High‐Intensity Focused Ultrasound (HIFU) therapy systems for real‐time image‐guided therapy that does not require any modification of a commercial imaging system. HIFU therapy with a duty cycle of 83% could be performed simultaneously with B‐mode imaging by combining 5 image frames to remove HIFU interference in the entire field of view, with an overall frame rate of 11 frames/s. In vivo experiments in rabbit thigh muscle showed that the volume of HIFU‐treated lesions increased by 342% (p<0.01) when the duty cycle was increased from 50% to 95% for the same HIFU treatment times. The HIFU treatment time required at 90% duty cycle was 64% less (p<0.05) than that required at a 50% duty cycle to create lesions of the same volume.
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28 March 2005
4TH INTERNATIONAL SYMPOSIUM ON THERAPEUTIC ULTRASOUND
18-20 September 2004
Kyoto (Japan)
Research Article|
March 28 2005
Real‐Time Ultrasound‐Guided High‐Intensity Focused Ultrasound Therapy with Enhanced Visualization and Reduced Treatment Time
Siddhartha Sikdar;
Siddhartha Sikdar
1Department of Electrical Engineering, University of Washington, Seattle, WA
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Vesna Zderic;
Vesna Zderic
2Applied Physics Laboratory, University of Washington, Seattle, WA
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Ravi Managuli;
Ravi Managuli
3Department of Bioengineering, University of Washington, Seattle, WA
4Hitachi Medical Systems America, Twinsburg, OH
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Shahram Vaezy;
Shahram Vaezy
2Applied Physics Laboratory, University of Washington, Seattle, WA
3Department of Bioengineering, University of Washington, Seattle, WA
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Yongmin Kim
Yongmin Kim
1Department of Electrical Engineering, University of Washington, Seattle, WA
3Department of Bioengineering, University of Washington, Seattle, WA
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AIP Conf. Proc. 754, 47–51 (2005)
Citation
Siddhartha Sikdar, Vesna Zderic, Ravi Managuli, Shahram Vaezy, Yongmin Kim; Real‐Time Ultrasound‐Guided High‐Intensity Focused Ultrasound Therapy with Enhanced Visualization and Reduced Treatment Time. AIP Conf. Proc. 28 March 2005; 754 (1): 47–51. https://doi.org/10.1063/1.1901597
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