The purpose of this research was to evaluate two methods for improving the accuracy rate of AD prediction in MRI images: AdaBoost (AB) and a novel convolutional neural network (CNN) technique. Materials and Methods: After being extracted from the ADNI database, the experimental data goes through a series of image preparation and feature extraction procedures. There were a total of 26 people included in the sample for the AD diagnosis; 13 from Group 1 and 13 from Group 2. Alpha and beta were used in the computation, along with a G-power of 0.8, values of 0.05 and 0.2, and a confidence range of 95%. In order to forecast the presence of Alzheimer’s disease in magnetic resonance imaging (MRI) scans, a combination of the innovative AdaBoost (AB) model and a Convolutional Neural Network (CNN) classifier using a large sample size (N=13) was employed. Results: The novel convolutional Neural Network (CNN) classifier outperforms the AdaBoost (AB) model, which achieved an accuracy rate of 82.96%, by a wide margin. Discussion and conclusion:-It was decided that p = 0.001 (p<0.05) was the level of significance for the inquiry. This provides more evidence that the test groups are distinct from one another. Finally, for MRI-based Alzheimer disease prediction, the novel convolutional Neural Network (CNN) classifier outperforms the AdaBoost (AB) with a higher accuracy of 93.78%.

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