Wood production has increased an average annual increase of 8.13% per year, with production figures reaching 2.6 million m3 and an average of 51% waste generated. With this high amount of waste, efforts need to be made to overcome it, with pyrolysis technology that can convert waste into products that have higher functionality and economic value. This research examines the potential of liquid smoke from the conversion of pine wood saw waste (Pinus merkusii) as a fungicide to control coffee rust disease caused by Hemileia vastatrix. The test parameters observed were an analysis of the chemical and physical characteristics of liquid smoke, in vivo studies by measuring the percentage incidence of disease, and in vitro studies by measuring the percentage of uredospore germination inhibition rate (% GIR) of coffee leaf rust disease. In this research, we compare the effectiveness of three different concentrations (0.25%; 0.5%; and 0.75%) of liquid smoke. From the GCMS analysis, antifungal compounds contained in liquid smoke include acetic acid, carboxylic acid, alcohol, ether, and phenols such as lactones, curcumin analogues, acetovanillone, eugenol, and guaiacol. Based on the results of research, the higher the concentration of liquid smoke the lowest the incidence of coffee rust diseases and the higher the GIR value (%). Based on statistical analysis, the lowest concentration of liquid smoke (0.25%) was still effective in minimizing the incidence of rust disease after 4 weeks of use and in inhibiting uredospore germination after 24 hours.

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