A visible spectroscopic method for the evaluation of cefadroxil in both its pure form and in pharmaceutical formulations. Fe+3 ion and cefadroxil undergo an oxidation-reduction process in the technique. Following the reaction between the released Fe+2 and 4,7-diphenyl-1,10-phenanthroline, a red complex with a maximum absorbance at 533 nm is created. There is a 2.833 x 104 L. mole-1. cm-1 molar absorptivity. Over a concentration range of (0.5-15 µg.ml−1), Beer’s law is observed. A reaction pathway was proposed after extensive research and optimization of several parameters that affect the growth and stability of color products. Cefadroxil in the capsule formulation was effectively identified using the suggested method. for the analysis of cefadroxil in pure form and pharmaceutical preparations was suggested.
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7 May 2024
FIFTH INTERNATIONAL CONFERENCE ON APPLIED SCIENCES: ICAS2023
26–27 August 2023
Baghdad, Iraq
Research Article|
May 07 2024
Utilizing the 4,7-diphenyl-1,10-phenanthroline reagent in the spectrophotometric method for cefadroxil determination
Amina Dawood;
Amina Dawood
a)
1
Chemistry Department, College of Science, University of Mosul
, Mosul, Iraq
a)Corresponding author: [email protected]
Search for other works by this author on:
Nabeel Othman
Nabeel Othman
b)
1
Chemistry Department, College of Science, University of Mosul
, Mosul, Iraq
Search for other works by this author on:
Amina Dawood
1,a)
Nabeel Othman
1,b)
1
Chemistry Department, College of Science, University of Mosul
, Mosul, Iraq
a)Corresponding author: [email protected]
AIP Conf. Proc. 3097, 030004 (2024)
Citation
Amina Dawood, Nabeel Othman; Utilizing the 4,7-diphenyl-1,10-phenanthroline reagent in the spectrophotometric method for cefadroxil determination. AIP Conf. Proc. 7 May 2024; 3097 (1): 030004. https://doi.org/10.1063/5.0209551
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