Mitigation strategies during the COVID-19 pandemic involve tracking and tracing the spread of the virus, monitoring vaccination status, and people’s mobility. In Indonesia, the PeduliLindungi application is used for this purpose. With the easing of social distancing rules from June to July 2022, PeduliLindungi is expected to act as a barrier to prevent a resurgence of the virus. Although using the application is mandatory before entering a public area, not everyone has been using it. Depok, an urban supporting area for Indonesia’s capital city, was sampled for this study, which aimed to investigate whether people’s knowledge of COVID-19 determined the app’s usage in the past month. The test results showed that most of the subjects used the application. Moreover, there was no significant difference in knowledge of COVID-19 between app users and non-users (p-value 0.445). The results suggest that the PeduliLindungi application plays a positive role in pandemic mitigation and is accessible to people with varying levels of knowledge about COVID-19.

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