This study includes pot experiment, using silty clay loam soil to evaluate the effect of three types of fertilizer, Bio fertilizer wich include soybean Rhizobia especilize as (Brady rhizobium Japonicum and Bacillus megaterium), Vermicompost and Mineral fertilizer on soybean growth, prouductivity and some soil properties after cultivation. The CRD application was connected with three replications. The first factor includes two Isolated Bacteria, Rhizobia and Bacillus the second factor was 8 Mg ha−1 of vermicompost (with and without). While the third factor was mineral fertilizer as complete recommendation (100N, 160 P2O5, 80 K2O) kg ha−1 and a half of complete recommendation. the inoculated soybean seeds were cultivated at 18-5-2021. The result shows that, the best treatment was at the two Isolated Bacteriata with Vermicompost and a half recommendation of Mineral fertilizer wich symbolize at (T8). This treatment improve some parameters of soybean growth, yield and gave significant effect in compare with separately addition of Isolated Bacteria, vermicompost and mineral fertilizer. This Interaction gave highest plant hight (89.8 cm), beast leaf area (68.4 dcm plant−1), highest dry weight (58.6 gm plant−1), highest dry root weight (12.8 gm plant−1), high number of pods (195.6 pod plant−1), highest number of pod seeds (2.96 seed pod−1) and Total yield (110.8 gm plant−1). the result also shows, significant effect of interaction between Isolated bacteria, vermicompost and half mineral fertilizer of complete recommendation decrease soil pH and Ec wich was (7.25 and 2.26 dsm−1), respectively. This treatment T8, also increase the Total Nitrogen value wich gave as percentage increase 198.2% available phosphear 28.7 ppm and available potassium 188.2 ppm. The increase in root nodules were showed in this treatment T8 wich obsarve 60.3 nodules plant−1, also there was increasing in O.M. percentage to 2.96%. T7 treatment (Isolated bacteria with vermicompost) followed T8 in those parameters. T4 and T6 alone or with half recommendation of complete mineral fertilizer followed by T7. T3 and T5 (Isolated bacteria alon and vermicompost alon) followed T7 and followed by T2 (miner fertilizer alone) and T1 (control) which gave lowest value in those Parameters.

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