Resistance of the Aedes aegypti mosquito to insecticides is a problem in preventing dengue fever. The combination of several insecticides is one way to prevent resistance. Commercial insecticides in the community offer various combinations of active substances. This study aims to determine the effectiveness of commercial domestic insecticides that consisting of one, two, and three active substances of insecticide. The susceptibility test of the Aedes aegypti mosquito in the Tamansari sub-district of Bandung City to domestic insecticides was carried out in November 2021. The susceptibility test of Aedes aegypti to each commercial insecticide was carried out using 6 glass tubes containing 25 of adult female Aedes aegypti per tube. Mosquitoes were exposed to commercial domestic insecticide for 60 minutes. The dosage used for test was according to the recommended use of commercial insecticides. After exposure, mosquitoes were transferred to another room with fresh air for 24 hours and fed sucrose solution. After 24 hours the proportion of knock out mosquitoes was calculated. The results showed that there were differences in the number of knock out mosquitoes on insecticides with one, two, or three active substances (p=0.04). Increasing the number of active substances did not increase the effectiveness of insecticides. The effectiveness of insecticides depends on the type and dose of insecticide, the susceptibility status of the mosquito, and the insecticide’s carrier.

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