Smoking has a profound effect on human health and can even be fatal. Smoking can have a negative impact on various blood parameters, leading due to an elevated risk of cardiovascular disease, inflammation, and weakened immune system. In this study, the effects of smoking were examined in relation to a number of criteria that are thought to be indicators of serious health issues in humans. Fifty male smokers from Iraq who had been smoking for at least ten years and who smoked at least ten cigarettes a day participated in the study in Samawah city. Vein was used to obtain the blood samples (5ml), which were then placed in non-heparinized tubes and dismissed at 3000 rpm for 15 minutes. Due to the sake of statistical comparison, the group consists of 25 male smokers, aged 25 to 55, and 25 male non-smokers, also recruited within the same age range. As a result of the study, blood measures such as hemoglobin (Hb), packed cell volume (PCV), red blood cells (RBC), white blood cells (WBC), and platelets all showed significant increases (PLT) in smokers participants in comparison with non-smokers. Taken together, Smoking has negative effects on blood parameters and could cause significant issues in humans.

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