Background. The strains of S. aureus especially (MRSA) are worldwide life-threating of health which continues to extend adaptation to antimicrobial agent due to virulence factor. Objective. The purpose of the study to determine antimicrobial sensitivity patterns among MRSA strains isolates from hospitalized patients with DFI. Methods. The present study involved 26 of pus/wound swab specimen collected from site of Diabetic Foot Infections (DFI). Results. The results clarified that 20(76.92%) MRSA isolates from the total 23 Staphylococcus aureus isolates, MRSA Strains have high degree of Antimicrobial Resistance reach to 100% for Cefamandole, Carpenicillin, Oxacillin, Amoxicillin, and Erythromycin. Conclusion. Multi-drug Resistant of MRSA isolates lead to increase virulence and risk factors in the diabetic foot ulcer lead to invasion of the infection and raise in morbidity and mortality of hospitalized patients.

1.
Richard
,
J.L.
,
Sotto
,
A.
and
Lavigne
,
J.P.
(
2011
). "
New insights in diabetic foot infection
".
World J. Diabetes.
15
:
24
32
.
2.
Spichler
,
A.
,
Hurwitz
,
B.L.
,
Armstronge
,
D.G.
and
Lipsky
,
B.A.
(
2015
). "
Microbiology of diabetic foot infections : from Louis Pasteur to crime scene investigation
".
BMC Med.
13
:
209
.
3.
Ababneh
,
A. N.
(
2021
). "
Adherence of Wearing Removable Cast Walkers in Patients with Diabetes-Related Foot Ulcers: A Mixed Methods Investigation
". Ph.D. Dissertation.
Queensland University of Technology
.
United States
. PP:
1
10
.
4.
Zahran
W. A.
,
Zein-Eldeen
A. A.
,
Hamam
S. S.
,
Elsayed-Sabal
M. S.
(
2017
).
Surgical site infections: problem of multidrug-resistant bacteria
.
Menoufia Medical Journal
;
30
(
4
):
1003
1012
.
5.
Vidhani
,
S.
,
Mehndiratta
,
P.L.
&
Mathur
,
M.D.
(
2001
). "
Study of Methicillin Resistant S. Aureus (MRSA) Isolates from High risk Patients
".
Indian Journal of Medical Microbiology.
19
(
2): 87-90
.
6.
Sarkisian
,
S. A.
(
2011
). "
Biofilm Production by Clinical Staphylococcus aureus and its Inhibition by Hypericum Metabolites
".
M.SC. Th. University of Rhode Island
.
U.S.A
. PP:
11
15
.
7.
Fraimow
,
H.S.
&
Tsigrelis
,
C.
(
2011
). "
Antimicrobial resistance in the intensive care unit: mechanism, epidemiology and management of specific resistant pathogens
".
Crit. Care. Clin.
,
27
(
1
):
163
-
205
.
8.
Mahon
,
C. R.
&
Lehman
,
D. C.
(
2019
). "
Text Book of Diagnostic Microbiology
". 6th ed.
Elsevier Inc
. PP:
800
1000
.
9.
Cappuccino
JG
,
Sherman
N
(
2014
). "
Microbiology: A laboratory manual
". 10th ed.
Pearson Education, Inc
.,
United States of America
;. pp.
150
300
.
10.
Clinical and Laboratory Standards Institute CLSI
. (
2016
). "
Performance Standards for Antimicrobial Susceptibility Testing
". 26th ed.
CLSI supplement M100S. Wayne, PA: Clinical and Laboratory Standards Institute.
36
(
1
):
20
240
.
11.
Abdulmageed
,
M. U.
,
Abdullah
,
A. A.
(
2019
).
Risk factors for postsurgical diabetic foot recurrence after minor or major lower-limb’s amputation
.
Mustansiriya Med J
;
18
:
85
91
.
12.
Al-Salihi
,
S. H.
, &
Jumaah
,
I. A. M.
(
2013
).
Bacterial infection of diabetic foot ulcer
.
Diyala Journal
,
9
,
15
21
.
13.
Azoury
,
S. C.
,
Farrow
,
N. E.
,
Hu
,
Q. L.
,
Soares
,
K. C.
,
Hicks
C.W.
,
Azar
,
F.
,
Unda
,
N. R.
,
Poruk
,
K. E.
,
Cornell
,
P.
,
Burce
,
K. K.
,
Cooney
,
C. M.
,
Nguyen
,
H.T.
&
Eeckhauser
,
F.
(
2015
). "
Postoperative abdominal wound infection – epidemiology, risk factors, identification, and management
".
Article of Chronic Wound Care Management and Research. U.S.A.
3
(
2
):
137
-
148
.
14.
Lipsky
,
B.A.
,
Berendt
,
A.R.
,
Deery
,
H.G.
,
Embil
,
J.M.
,
Joseph
,
W.S.
,
Karchmer
,
A.W.
,
Lefrock
,
J.L.
,
Lew
,
D.P.
,
Marder
,
J.T.
,
Norden
,
C.
, and
Tan
,
J.S.
(
2004
). "
Diagnosis and treatment of diabetic foot infection
".
Clinical Infectious Diseases.
l39
(
1
):
885
910
.
15.
Bergman
,
S.
,
Pharm
,
D.
&
Shah
,
P. J.
,
Pharm
,
D.
(
2016
). "
Diabetic Foot Infections
".
Infection Primary Care. Book.
3
.
ACSAP
. PP:
8
26
.
16.
Ozan
,
F.
,
Gürbüzi
,
K.
,
Çelik
,
İ.
,
Dursun
,
Z.B.
&
Uzun
,
E.
(
2017
). "
Evaluation of major and minor lower extremity amputation in diabetic foot patients
".
Turkish Journal of Medical Sciences.
47
:
1109
1116
.
17.
Kandala
,
N. J.
,
Abdulateef
,
M.
&
Imad
,
N.
(
2017
). "
Genotyping of Staphylococcus aureus Isolates Based on Methicillin-Resistance Genes and its Relatedness to some Putative Virulence Factors
".
Journal of Science.
58
(
2
):
626
638
.
18.
Baker
,
M.
,
Hobman
,
J. L.
,
Dodd
,
C. E. R.
,
Ramsden
,
S. J.
&
Stekel
,
D. J.
(
2016
). "
Mathematical modelling of antimicrobial resistance in agricultural waste highlights importance of gene transfer rate
."
FEMS Microbiol.
92
(
4
):
1
32
.
19.
Khaleel
,
D. A.
,
Othman
,
R.M.
&
Khudaier
,
B.Y.
(
2018
). "
Plasmid transformation and curing of nalidixic acid gene in Staphylococcus aureus isolated from buffaloes mastitis and worker’s hands
".
Iraqi Journal of Veterinary Sciences.
32
(
2
):
167
174
.
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