Oxidative damage can cause various degenerative diseases. Degenerative diseases can be exacerbated by deadly infectious diseases. Groups of compounds and natural products that have antioxidant and antibacterial properties can inhibit oxidative damage and infectious diseases. The development of natural products that have the potential as antioxidant and antibacterial agents is a continuous effort in the field of drug discovery. This study aims to explore the potential of Lampung robusta coffee as a nature-based antioxidant and antibacterial agent. Identification of the active compound of the test extract was carried out qualitatively using a reagent solution. Antioxidant potential test using the DPPH method (2,2-Diphenyl-1-Picrylhydrazil). The test samples were made with various levels of 20 g/ml; 40 g/ml, 60 g/ml; 80 g/ml and 100 g/ml. Antibacterial test against several strains (S. aureus; P. aeruginosa) using disc diffusion method. The test extract has antioxidant power with IC50 (Inhibitory Concentration) of 121.45+18.62 g/ml. The total phenolic content of the test extract was 539.03+28.02 mg gallic acid equivalent/g sample. The test extract did not show the diameter zone of inhibition in the antibacterial test. This research can provide scientific evidence of the antioxidant and antibacterial potential of Lampung robusta coffee so that it can become a useful product in society based on science and can be accounted for for its efficacy.
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5 September 2024
THE 4TH INTERNATIONAL CONFERENCE ON APPLIED SCIENCES, MATHEMATICS, AND INFORMATICS: ICASMI2022
8–9 September 2022
Bandar Lampung, Indonesia
Research Article|
September 05 2024
Exploration of potential antioxidant and antibacterial activities of Lampung robusta coffee ethanolic extracts
Muhammad Iqbal;
Muhammad Iqbal
a)
1
Faculty of Medicine, University of Lampung
Jl. Prof. Dr. Ir. Sumantri Brojonegoro, Bandarlampung, Lampung 35141, Indonesia
a)Corresponding author: [email protected]
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Ramadhan Triyandi
Ramadhan Triyandi
b)
1
Faculty of Medicine, University of Lampung
Jl. Prof. Dr. Ir. Sumantri Brojonegoro, Bandarlampung, Lampung 35141, Indonesia
Search for other works by this author on:
a)Corresponding author: [email protected]
AIP Conf. Proc. 2970, 060041 (2024)
Citation
Muhammad Iqbal, Ramadhan Triyandi; Exploration of potential antioxidant and antibacterial activities of Lampung robusta coffee ethanolic extracts. AIP Conf. Proc. 5 September 2024; 2970 (1): 060041. https://doi.org/10.1063/5.0208216
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