Antibiotic resistance is on the rise, caused by infectious infectious diseases, which account for half of all deaths worldwide. Pseudomonas aeruginosa Gram-negative and Staphylococcus aureus Gram-positive bacteria. It is a serious human pathogen with few symptoms, Infection from the environment and hospitals and treatment is difficult due to the multidrug-resistant form of MRSA (Methicillin-Resistant Staphylococcus aureus). Kangkong is a commercially important vegetable that thrives in humid areas from the subtropics to temperate zones and has a high tolerance for high temperatures. Kangkong contains vitamins and minerals such as water, protein, fat, carbohydrates, calcium calories, potassium iron, vitamin C, vitamin A and vitamin B. The purpose of this study was to determine the total phenolic content, antioxidant activity and antibacterial activity of ethanol extract of kangkung root using the reflux method. The results of this study showed that the ethanol extract of Ipomoea reptans (Linn) Poir root had a total phenolic value of 251.59±38.32, an antioxidant activity of 480.8042±30.9290, and no antibacterial activity against Staphylococcus aureus and Pseudomonas aeruginosa bacteria.
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