Aim: To investigate the sodium atom movie potential to divert impacts in atrial center Electrocardiogram (ECG) age for the norm and remarkable condition utilizing Rungekutta system. Materials and Methods: In this research human atrial cells are based on Seemann et al. method can be used to describe the action potential model of sinoatrial nodes. Sample size can be calculated as 70 and the G power is 80%. Results: The conventional film capacity of sodium is 81.2 mV, but for the different abnormal values of 100%, half and 25%, then the membrane potentials are 162.4 mV, 121.8 mV and 101.5 mV and thereafter the reducing of 100% sodium levels doesn’t outline single ECG waveform, decreasing of half and 25%, the membrane potentials are 40 mV and 37.7 mV. By taking a gander at these characteristics there is a differentiation in pacemaking development and causes capricious heart beat and prolongation occurs. Conclusion: In common place Action Potential, the withdrawal will happen reliably. In strange AP, the conduction of electrical excitation will change and make erratic heart work cause arrhythmia. A predominant perception of the cell model can be used to perceive the prescription that helps with making a regular heart beat.
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7 May 2024
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Research Article|
May 07 2024
Computational model based approach to analyse pacemaking activity of sinoatrial node due to sodium channels using rungekutta method
D. Yamuna;
D. Yamuna
1
Department of Biomedical Engineering, Saveetha School of Engineering, SIMATS
, Chennai, Tamilnadu, India
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Arulvel Ramaswamy;
Arulvel Ramaswamy
2
Department of Biotechnology, Saveetha School of Engineering, SIMATS
, Chennai, Tamilnadu, India
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G. Gulothungan;
G. Gulothungan
a)
1
Department of Biomedical Engineering, Saveetha School of Engineering, SIMATS
, Chennai, Tamilnadu, India
a)Corresponding author: [email protected]
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T. Sathish
T. Sathish
3
Department of Mechanical Engineering, Saveetha School of Engineering, SIMATS
, Chennai, Tamilnadu, India
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a)Corresponding author: [email protected]
AIP Conf. Proc. 2853, 020121 (2024)
Citation
D. Yamuna, Arulvel Ramaswamy, G. Gulothungan, T. Sathish; Computational model based approach to analyse pacemaking activity of sinoatrial node due to sodium channels using rungekutta method. AIP Conf. Proc. 7 May 2024; 2853 (1): 020121. https://doi.org/10.1063/5.0198048
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