Fluorescence spectroscopy is one of the sensitive techniques for the detection of biochemical changes occur due to cancer and many other pathological conditions. A portable device based on fluorescence spectroscopy has been tested on total of 117 biopsy samples which includes 29 normal, 72 cervical intraepithelial neoplasia I (CIN I), and 16 CIN II cervical tissue samples. A multistep algorithm has been used and different grades are discriminated from normal samples with high sensitivity and specificity. The results of the study indicates that the fluorescence spectroscopy based techniques can be an alternative for the detection of cancer at an early stage.

Topics
Fluorescence spectroscopy, Diseases and conditions, Medical diagnosis
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