On the other hand, cassava leather contain antimicrobial compounds that can be used to reduce microbial contamination. This research aimed to determine active compound of Manalagi cassava leather by analysis using GC-MS. Therefore in this research, we aimed to study whether antimicrobial activity of extracts of cassava leather and leaves by GCMS. The result research showed that the most dominant compounds by analysis using GC-MS CP-3800 are Propane,1,1,3-trietoxy-(3,17%); 2,3-Dihydro-3,5-dihydroxy-6-methyl-4H-pyran-4-one (2,97%); 2-furancarboxaldehyde, 5-(hydroxymethyl)-(21,29%); alpha. -D-Glucopyranoside, .alpha. -D-glucopyranosyl (56,61%); Propane,1,1,3-trietoxy-(3,17%) and Cholestan-22(26)-isoepoxy-3,16-dione (1,83%). alpha-D-glucopyranosyl; Propane,1,1,3-trietoxy-; and 2-furancarboxaldehyde, 5-(hydroxymethyl). alpha. -D-Glucopyranoside, .alpha. -D-glucopyranosyl and 2-furancarboxaldehyde, 5-(hydroxymethyl)-Compounds of cassava leather are secondary metabolites that play a role as an antimicrobial.

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