Molecularly Imprinted Polymers (MIPs) have been synthesized and can be used as uric acid absorbent in samples. MIPs can absorb uric acid because MIPs have cavities were formed by the removal of uric acid. The purpose of this research was to determine the synthesis, characteristics of MIPs membrane, and MIPs absorption for uric acid at optimum conditions. The method used for the synthesis of MIPs membrane is the photopolymerization method using Ultra-Violet light. Determination of uric acid levels in solution was analyzed by spectrophotometer UV-Vis and in blood by Easy Touch. Based on the research obtained a transparent uric acid MIPs membrane. The result of the FTIR spectrum analysis showed that the infrared spectra characterization of the MIPs-extraction membrane did not find N-H absorption peak, while in the MIPs re-extraction there was an absorption peak in the 910-665. The N-H group is the functional group of uric acid. Based on absorption under optimum conditions the number of MIPs membrane used was 0.08 grams with contact time of 24 hours and pH of 7.57 uric acid solution obtained the efficiency of MIPs absorption in solution was 72.6%, while the efficiency of MIPs absorption of uric acid in the blood was 24.6 %. The result of this study indicate that the MIPs membrane can absorb uric acid both in solution and in blood.
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24 April 2023
THE 2ND INTERNATIONAL CONFERENCE ON CHEMISTRY AND SCIENCE EDUCATION: Improving the Research Quality in Chemistry and Natural Science Education for The Upcoming Challenges to Face The 5th Industrial Revolution
4–5 August 2021
Padang, Indonesia
Research Article|
April 24 2023
Optimization of molecularly imprinted polymers (MIPs) membrane absorption for uric acid
Nurhafizah Azwir;
Nurhafizah Azwir
a)
Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang
, Jl. Prof. Hamka, Padang 25131, Indonesia
a)Corresponding author: alizarchem@yahoo.co.id
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Alizar Ulianas;
Alizar Ulianas
Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang
, Jl. Prof. Hamka, Padang 25131, Indonesia
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Wahyudi;
Wahyudi
Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang
, Jl. Prof. Hamka, Padang 25131, Indonesia
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Nabila Nurul Ain;
Nabila Nurul Ain
Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang
, Jl. Prof. Hamka, Padang 25131, Indonesia
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Indah Gusti Fauzi
Indah Gusti Fauzi
Department of Chemistry, Faculty of Mathematics and Natural Science, Universitas Negeri Padang
, Jl. Prof. Hamka, Padang 25131, Indonesia
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a)Corresponding author: alizarchem@yahoo.co.id
AIP Conf. Proc. 2673, 060004 (2023)
Citation
Nurhafizah Azwir, Alizar Ulianas, Wahyudi, Nabila Nurul Ain, Indah Gusti Fauzi; Optimization of molecularly imprinted polymers (MIPs) membrane absorption for uric acid. AIP Conf. Proc. 24 April 2023; 2673 (1): 060004. https://doi.org/10.1063/5.0126882
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