Phytophthora capsici L. is a fungus that causes stem rot in pepper plants. The provision of synthetic pesticides to control plants leaves residues that are harmful to the environment and human health. The plant-based fungicides are environmentally friendly and can be used as an alternative. The purpose of this study was to extract red galangal rhizome (Alpinia purpurata K.Schum) and determine its inhibitory activity against Phytophthora capsici L. In addition, identification of the active compounds contained in red galangal extract was carried out. The extraction method used is maceration and fractionation using vacuum liquid chromatography obtaining n-hexane fraction, ethyl acetate fraction , and ethanol fraction. The extract and fractions were determined their inhibitory activity against Phytopthora capsici L. The results showed that ethanol extract, ethyl acetate fraction, and ethanol fraction of red galangal were proven to inhibit the growth of the fungus Phytophthora capsici L. at any concentration. The best inhibitory activity of the fungus Phytophthora capsici L. was achieved by the ethyl acetate fraction at a concentration of 1.5% with an inhibition percentage value of 92.41% and classified as a very high activity level. Compounds that have the potential as antifungals in red galangal rhizome are flavonoids, saponins, phenolics, and terpenoids.

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