The article presents the results of a study aimed at improving the safety of hemostatic parameters of donor fresh frozen blood plasma in its preparation for transfusion. The developed method of technological optimization of the process of preparation of fresh frozen blood plasma for transfusion in devices for its heat treatment is described and the results of its testing are presented. The results indicate that the use of the developed method of technological optimization of the process of preparation of fresh frozen blood plasma for transfusion leads to a reduction in the time of exposure on blood plasma in the device for its heat treatment, thereby potentially reducing the decrease in indicators of its thermolabile components. It is reasonable to continue the study to quantify the increase in their preservation with paired blood plasma samples obtained from the same donor.

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