Nanoparticles have many applications in the biomedical field primarily for drug delivery, cancer therapy, and detection of pathogenic microorganisms. In this study, Nano-pomegranate extract synthesized using pomegranate (peel) extract prepared by Sol-gel Nano-technique by ultrasonic pyrolysis method in aqueous solution at a temperature (0-80)°C to evaluated for their antibacterial potential and antioxidant . The morphology and size of the Nano-pomegranate extract were further characterized as spherical in shape with an average size of 58.10 nm in diameter by scanning electron microscopy and transmission electron microscopy. EDX analysis clearly displayed the presence of two high signal (sodium and carbon ) with different element (C,O,AL,Si,cl and Mg). The size of Nano-pomegranate was determined as 26 nm in the dominate peak (40.583) in reflections were confirmed by X-ray diffraction and X-ray photoelectron spectroscopy. In other way, Nano-extract given orally for 4 weeks in 3 concentration (0.1,0.05 &0.025)ml/kg b.w. the result indicated that Nano extract didn’t show any mortality or behavioral changes during the long period of treatment due to higher content of antioxidant compounds like different active ingredient phenolic compounds, flavonoids, carbohydrate, tannin and saponin. The synthesized Nano-pomegranate exhibited efficient antibacterial activity against Escherichia coli (28 mm) and Staph. aureus (28 mm) compared to crude extract and was (24)mm and (25) mm.
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8 November 2022
1ST SAMARRA INTERNATIONAL CONFERENCE FOR PURE AND APPLIED SCIENCES (SICPS2021): SICPS2021
23–24 March 2021
Samarra, Iraq
Research Article|
November 08 2022
Green synthesis of pomegranate peel extract nanoparticles; characterization and antioxidant activity
Awatif Ibrahim Mohammed;
Awatif Ibrahim Mohammed
a)
1
Veterinary Drug Center, Corporation of Research and Industrial Developmental, Ministry of Industrial &Minerals
, Baghdad, Iraq
a)Corresponding author: [email protected]
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Quraish A. Kahdhum;
Quraish A. Kahdhum
2
Chemical & Petrochemical Research Centre, Corporation of Research and Industrial Development, Ministry of Industry and Minerals
, Baghdad, Iraq
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Rana A. Kamal;
Rana A. Kamal
1
Veterinary Drug Center, Corporation of Research and Industrial Developmental, Ministry of Industrial &Minerals
, Baghdad, Iraq
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Ahmed J. Essa;
Ahmed J. Essa
1
Veterinary Drug Center, Corporation of Research and Industrial Developmental, Ministry of Industrial &Minerals
, Baghdad, Iraq
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Maan A. Abd elhamid;
Maan A. Abd elhamid
2
Chemical & Petrochemical Research Centre, Corporation of Research and Industrial Development, Ministry of Industry and Minerals
, Baghdad, Iraq
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Safaa Abd;
Safaa Abd
3
AL-Razi Research Centre , Corporation of Research and Industrial Developmental, Ministry of Industrial and Minerals
, Baghdad, Iraq
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Dalia M. Hassan;
Dalia M. Hassan
3
AL-Razi Research Centre , Corporation of Research and Industrial Developmental, Ministry of Industrial and Minerals
, Baghdad, Iraq
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Salma A. Abod
Salma A. Abod
1
Veterinary Drug Center, Corporation of Research and Industrial Developmental, Ministry of Industrial &Minerals
, Baghdad, Iraq
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a)Corresponding author: [email protected]
AIP Conf. Proc. 2394, 080001 (2022)
Citation
Awatif Ibrahim Mohammed, Quraish A. Kahdhum, Rana A. Kamal, Ahmed J. Essa, Maan A. Abd elhamid, Safaa Abd, Dalia M. Hassan, Salma A. Abod; Green synthesis of pomegranate peel extract nanoparticles; characterization and antioxidant activity. AIP Conf. Proc. 8 November 2022; 2394 (1): 080001. https://doi.org/10.1063/5.0121388
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