The current study was conducted to study the therapeutic effect lemongrass leaves aqueous extract on some biochemical parameters of domestic male rabbits with experimentally induced arteriosclerosis by giving them a standard diet added to it with cholesterol powder at a concentration (1 g / kg diet). 40 male rabbits used in current work and distributed as follow (10 rabbits in each group): control group. The second group: male rabbits feeding on high cholesterol diet for 21 days. The third group: rabbits with atherosclerosis and then treated with (200 mg/kg/daily) aqueous extract for 30 days. The fourth group: rabbits with atherosclerosis and then treated with rosuvastatin at a concentration (1 mg / kg/ daily) for a period of 30 days. The results of the current study showed a significant (P<0.05) increase in the levels of TC, TG, LDL-C, VLDL-C, urea and creatinine levels and significant (P<0.05) decrease in the levels of total protein, albumin, globulin, glutathione and glutathione peroxide in the second group compared with control group. After treatment with aqueous extract of lemongrass (third group) and rosuvastatin (fourth group), the lipid profile, kidney function parameters and antioxidant enzymes show improvement compared with second group.

Topics
Electrolytes, Free radicals, Enzymes, Organs, Lipids, Atherosclerosis, Cholesterol, Globular protein
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