Burns, which generate hypertrophic scar formation, may decrease functional and aesthetical aspects of patients’ quality of life. To date, grafting treatments were not only proceeded solitarily. The technological development of burn treatments emerged with approaches, such as negative pressure wound therapy (NPWT) and tissue-engineered skin (TES). By incorporating negative pressure on the wound bed, NPWT was able to remove debris, remove exudates, maintain humidity, and improve epithelization. A latter development of wound management, TES, also showed prominent results of wound healing. Benefitting from tissue engineering approaches, TES provided the wound bed with extracellular matrix (ECM) and 3D structure to support wound healing. In some reports, NPWT was combined with TES to promote better efficacy. Unfortunately, the efficacies of NPWT, TES, or NPWT-TES hybrid as assisting approaches for skin drafting techniques are not reviewed yet, as well as the cost comparison of the three treatments. In this report, the comparison of skin grafting techniques assisted with the three treatments (NPWT, TES, or NPWT-TES hybrid) was investigated in terms of efficacy and cost. The review starts with brief technical aspects of the three treatments. Subsequently, the efficacy and cost analyses were discussed.
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23 March 2021
THE 5TH BIOMEDICAL ENGINEERING’S RECENT PROGRESS IN BIOMATERIALS, DRUGS DEVELOPMENT, AND MEDICAL DEVICES: Proceedings of the 5th International Symposium of Biomedical Engineering (ISBE) 2020
28–29 July 2020
Depok, Indonesia
Research Article|
March 23 2021
Cost-efficacy of skin grafting techniques using negative pressure wound therapy and tissue-engineered skin for burns
Muhammad Hanif Nadhif;
Muhammad Hanif Nadhif
1
Department of Medical Physics, Faculty of Medicine, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
2
Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
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Muhammad Satrio Utomo;
Muhammad Satrio Utomo
1
Department of Medical Physics, Faculty of Medicine, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
2
Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
3
Research Center for Metallurgy and Materials, Indonesian Institute of Sciences
, PUSPIPTEK Building 470, South Tangerang, Banten 15314 Indonesia
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Muhammad Farel Ferian;
Muhammad Farel Ferian
4
Undergraduate Program, Faculty of Medicine, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
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Farhan H. Taufikulhakim;
Farhan H. Taufikulhakim
4
Undergraduate Program, Faculty of Medicine, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
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Nadine H. P. Soerojo;
Nadine H. P. Soerojo
4
Undergraduate Program, Faculty of Medicine, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
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Muhammad Dzulkarnaen Nain;
Muhammad Dzulkarnaen Nain
4
Undergraduate Program, Faculty of Medicine, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
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Prasandhya A. Yusuf;
Prasandhya A. Yusuf
a)
1
Department of Medical Physics, Faculty of Medicine, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
2
Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
a)Corresponding author: prasandhya.a.yusuf@ui.ac.id
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Anindya P. Susanto;
Anindya P. Susanto
1
Department of Medical Physics, Faculty of Medicine, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
2
Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
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Theddeus O.H. Prasetyono
Theddeus O.H. Prasetyono
2
Medical Technology Cluster, Indonesian Medical Education and Research Institute, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
5
Division of Plastic Surgery, Department of Surgery, Cipto Mangunkusumo Central Hospital/Faculty of Medicine, Universitas Indonesia
, Jl. Salemba Raya No. 6, Central Jakarta, DKI Jakarta 10430 Indonesia
6
Indonesian Clinical Training and Education Centre (ICTEC), Cipto Mangunkusumo Central Hospital
, Jl. Pangeran Diponegoro No. 71, Senen, Central Jakarta, DKI Jakarta 10430 Indonesia
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a)Corresponding author: prasandhya.a.yusuf@ui.ac.id
AIP Conf. Proc. 2344, 050008 (2021)
Citation
Muhammad Hanif Nadhif, Muhammad Satrio Utomo, Muhammad Farel Ferian, Farhan H. Taufikulhakim, Nadine H. P. Soerojo, Muhammad Dzulkarnaen Nain, Prasandhya A. Yusuf, Anindya P. Susanto, Theddeus O.H. Prasetyono; Cost-efficacy of skin grafting techniques using negative pressure wound therapy and tissue-engineered skin for burns. AIP Conf. Proc. 23 March 2021; 2344 (1): 050008. https://doi.org/10.1063/5.0047187
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