Abnormal concentrations of dopamine in extracellular fluid are associated with a variety of diseases, such as Parkinson’s disease. It, therefore, plays a critical role in the quantitative analysis of dopamine in body fluids in the control of biological drugs as well as in the clinical diagnostic field. Poly (3,4-ethylenedioxythiophene)-(Poly(4-styrenesulfonate)) was successfully fabricated on the surface of the glassy carbon electrode by electrochemical method and used to determine dopamine. The oxidation peaks of dopamine had higher sensitivity at PEDOT-PSS modified electrode in phosphate buffer solution (PBS, pH 6.0). The electrocatalytic activity of the corresponding dopamine electrodes was investigated using cyclic voltammetry (CV) and indicated that PEDOT: PSS by electropolymerization modified had a much higher electrocatalytic oxidation activity for dopamine than any other method. The results obtained have shown that PEDOT: PSS is a promising candidate for the modification of electrode material used in electrochemical sensing and other electrocatalytic applications.

1.
J. E. F.
Reynolds
,
The Pharmaceutical Press
,
London
1993
, pp.
466
472
.
2.
Y.
Misu
,
Y.
Goshima
,
CRC Press
,
London
,
2005
, pp.
261
269
.
3.
A.
Barbeau
,
The Lancet.
,
1971
,
297
(
7695
)
395
4.
E.
Cubo
,
C. G.
Goetz
,
Academic press
,
USA
,
2003
, pp.
820
825
.
5.
H.
Ito
,
H.
Kawaguchi
,
F.
Kodaka
,
H.
Takuwa
,
Y.
Ikoma
,
H.
Shimada
,
Y.
Kimura
,
C.
Seki
,
H.
Kubo
,
S.
Ishii
and
H.
Takano
,
NeuroImage
,
158
(
2017
), pp.
12
17
.
6.
E.E. Ferapontova
Electrochim
.
Acta
,
245
(
2017
)
664
.
7.
M.
Arvand
,
G.
Navid
,
Sens. Actuators, B: Chem.
,
2014
,
204
(
12
), pp.
393
401
.
8.
M. M.
Ardakani
,
A.
Khoshroo
,
L.
Hosseinzadeh
.
Sens. Actuators, B: Chem.
,
2014
,
204
(
12
), pp.
282
288
.
9.
S. Y.
Yi
,
J. H.
Lee
,
H. G.
Hong
,
J Appl Electrochem.
,
2014
,
44
(
5
), pp.
589
597
.
10.
U.
Lange
,
N. V.
Roznyatovskaya
,
V. M.
Mirsky
,
Anal. Chim. Acta.
,
2008
,
614
(
1
), pp.
1
26
11.
C.
Li
,
H.
Bai
,
G.
Shi
,
Chem. Soc. Rev.
,
2009
,
38
(
8
), pp.
2397
2409
.
12.
J.
Janata
,
M.
Josowicz
,
Nat. Mater.
,
2003
,
2
(
1
), pp.
19
24
.
13.
M.
Ates
,
A.S.
Sarac
,
Prog. Org. Coat.
,
2009
,
66
(
4
), pp.
337
358
.
14.
D.
Kul
,
C. M. A.
Brett
,
Electroanalysis.
,
2014
,
26
(
6
), pp.
1320
1325
.
15.
B.
Fan
,
X.
Mei
,
J.
Ouyang
,
Macromolecules.
,
2008
,
41
(
16
), pp.
5971
5973
.
16.
R. R.
Smith
,
A. P.
Smith
,
J. T.
Stricker
,
B. E.
Taylor
,
M. F.
Durstock
,
Macromolecules.
,
2006
,
39
(
18
), pp.
6071
6074
.
17.
M.
Nikolou
,
G. G.
Malliaras
,
Chem. Rec.
,
2008
,
8
(
1
), pp.
13
22
.
18.
F.
Louwet
,
L.
Groenendaal
,
J.
Dhaen
,
J.
Manca
,
J. V.
Luppen
,
E.
Verdonck
,
L.
Leenders
,
Synth. Met.
,
2003
,
135
(
1-8
), pp.
115
117
.
19.
L. X.
Xiao
,
H.
Fei
,
L. Z.
Guo
,
Z.
Song
,
L. K.
Ji
,
MDPI
,
2010
,
10
, pp.
8398
8410
20.
J. G.
Manjunatha
,
B. E. Kumara
Swamy
,
M.
Deraman
,
G. P.
Mamtha
,
Int. J. Pharm. Sci.
2013
,
5
, pp.
355
361
.
21.
T.E. Mary
Nancy
,
V.
Anithakumary
,
B.E. Kumara
Swamy
,
Journal of Electroanalytical Chemistry
, pp.
2014
,
702-721
,
107
114
.
22.
S. F.
Rahman
,
K.
Min
,
S-H.
Park
,
J-H.
Park
,
J. C.
Yoo
,
D-H.
Park
,
Biotechnol Bioproc E.
2016
,
21
, pp.
627
633
.
23.
S. F.
Rahman
,
K.
Min
,
S-H.
Park
,
J-H.
Park
,
J. C.
Yoo
,
D-H.
Park
,
Korean J. Chem. Eng.
2016
,
33
,
342
3447
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