Ruta angustifolia is a medicinal plant often used in treating various diseases. Several studies have been carried out to reveal the chemical compounds in this plant, and some are effectively used as antimicrobials. Candida albicans is the most common pathogenic fungus in humans and causes many cases of infection. C. albicans can form biofilms on biotic and abiotic surfaces, either as mono or multispecies, that may increase its pathogenicity. In a state of forming biofilms, microbes are surrounded by an extracellular matrix that protects the microbial community from antimicrobial agents. In this study, we examined the effect of R. angustifolia extract on C. albicans biofilm formation. C. albicans preformed biofilms (24 h) were treated with various concentrations of R. angustifolia extract (100%, 50%, 20%) and incubated at 37°C for 24 h. The characteristics of biofilm formation were assessed with microscopic methods using a light microscope. The results indicated that the effect of R. angustifolia extract could inhibit the C. albicans hypha formation at all concentrations treated.
Skip Nav Destination
Article navigation
2 April 2021
THE 2ND SCIENCE AND MATHEMATICS INTERNATIONAL CONFERENCE (SMIC 2020): Transforming Research and Education of Science and Mathematics in the Digital Age
8–9 August 2020
Jakarta, Indonesia
Research Article|
April 02 2021
Inhibition of Candida albicans hypha formation in biofilm formation by Ruta angustifolia extract
Shafa Noer;
Shafa Noer
a)
1
Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia
, Depok 16424, Indonesia
3
Department of Biological Education, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indraprasta PGRI
, Jakarta 13760, Indonesia
a)Corresponding author: shafa_noer@yahoo.co.id
Search for other works by this author on:
Abinawanto;
Abinawanto
b)
1
Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia
, Depok 16424, Indonesia
Search for other works by this author on:
Boy M. Bachtiar;
Boy M. Bachtiar
2
Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia
, Jakarta 10430, Indonesia
Search for other works by this author on:
Anom Bowolaksono
Anom Bowolaksono
1
Department of Biology, Faculty of Mathematics and Natural Sciences (FMIPA), Universitas Indonesia
, Depok 16424, Indonesia
Search for other works by this author on:
a)Corresponding author: shafa_noer@yahoo.co.id
AIP Conf. Proc. 2331, 050003 (2021)
Citation
Shafa Noer, Abinawanto, Boy M. Bachtiar, Anom Bowolaksono; Inhibition of Candida albicans hypha formation in biofilm formation by Ruta angustifolia extract. AIP Conf. Proc. 2 April 2021; 2331 (1): 050003. https://doi.org/10.1063/5.0041682
Download citation file:
Sign in
Don't already have an account? Register
Sign In
You could not be signed in. Please check your credentials and make sure you have an active account and try again.
Could not validate captcha. Please try again.
Sign in via your Institution
Sign in via your InstitutionPay-Per-View Access
$40.00
Citing articles via
Related Content
Molecular identification of the medicinal herb plant Ruta angustifolia from Lembang Bandung using chloroplast DNA markers
AIP Conference Proceedings (October 2018)
Rheology of Candida albicans fungal biofilms
Journal of Rheology (July 2022)
Combatting fungal biofilm formation by diffusive release of fluconazole from heptylamine plasma polymer coating
Biointerphases (December 2020)
Fungal screening of women shoulder handbags with special reference to get rid of Aspergillus niger via essential oil vapours
AIP Conference Proceedings (October 2022)
Isolation of Candida albicans causing diaper rash and its sensitivity to pomegranate peel extract
AIP Conference Proceedings (April 2023)