Intracellular calcium plays an important role in controlling cellular activities. A fluctuation of intracellular calcium level occurs continuously in the living cells due to the function of different physiological activities. Calcium is a signalling molecule. Different calcium regulating channels are present on the plasma membrane and virus uses these channels for modulation of calcium in the intracellular level in their favour. The virus uses the genetic machinery of a cell for viral multiplication and also for transmission of infection. Calcium modulating therapeutic agents alters the signalling mechanism and this chemical might be a therap eutic chemical for control of viral highjack of the cellular mechanism of viral multiplication. Neuropeptide Y, an endogenous peptide has a wide scope of application as therapy to maintain or rejuvinate calcium modulating effect in the cell. This peptide may be applied to prevent viral entry in to the cells and thus blocks the highjack of normal cellular mechanisms.

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