In the present study antimicrobial property of intracanal medicament (ICM) containing oregano essential oil (OEO) were assessed. Intracanal medicament containing oregano essential oil were prepared at two concentrations of 25% (F1) and 50% (F2). Minimum inhibitory activity of the essential oil against bacteria and fungi were assessed by microbroth dilution method. Antimicrobial activity of the formulations and standards were tested against Prevotella. Intermedia, Enterococcus fecalis and Candida albicans by well diffusion method. Minimum Inhibitory Concentration of ciprofloxacin and OEO against P. intermedia, showed 0.25ug/ml and 25ug/ml; against E. fecalis were 0.5ug/ml and 25ug/ml respectively. MIC of itraconazole and OEO against C. albicans were 6.25ug/ml and 12.5ug.ml, respectively. Antimicrobial activity of ICM containing 25% (F1) and 50% (F2) concentration of OEO was assessed. Inhibitory activity of F1 and F2 showed lesser zone of inhibition against both P. intermedia and E. fecalis as compared to standard. F1 showed 26mm and F2 showed 22mm of zone of inhibition against C.albicans, which is lesser than standard, 30mm. In case of E.fecalis F1 showed 24mm and F2 showed 16mm of zone of inhibition in comparison to the zone of inhibition of standard 30mm. For the inhibitory activity against P.intermedia, F1 showed 24mm and F2 showed 13mm with standard 35mm zone of inhibition. The study reveals that F1 is more effective in eliminating secondary infections that are caused by C. albicans during endodontic treatment. F1 and F2 can also be used to treat infections caused by E. fecalis and P.intermedia with lesser action compared to standard.
Skip Nav Destination
Article navigation
5 October 2020
PROCEEDINGS OF INTERNATIONAL CONFERENCE ON ADVANCES IN MATERIALS RESEARCH (ICAMR - 2019)
25–27 July 2019
Bangalore, India
Research Article|
October 05 2020
Formulation and antimicrobial assessment of intracanal medicament containing oregano essential oil
Shreya Johari;
Shreya Johari
a)
1
Departtment of Pedodontics and Preventive Dentistry, Faculty of Dental Sciences, M. S. Ramaiah University of Applied Sciences
, Bangalore-560 054, INDIA
a)Corresponding Author: sjohari037@gmail.com;
Search for other works by this author on:
C. Pushpalatha;
C. Pushpalatha
b)
1
Departtment of Pedodontics and Preventive Dentistry, Faculty of Dental Sciences, M. S. Ramaiah University of Applied Sciences
, Bangalore-560 054, INDIA
Search for other works by this author on:
R. Deveswaran
R. Deveswaran
c)
2
Drug Design and Development Centre and Department of Pharmaceutics, Faculty of Pharmacy, M.S. Ramaiah University of Applied Sciences
, Bangalore-560 054, INDIA
Search for other works by this author on:
a)Corresponding Author: sjohari037@gmail.com;
AIP Conf. Proc. 2274, 050007 (2020)
Citation
Shreya Johari, C. Pushpalatha, R. Deveswaran; Formulation and antimicrobial assessment of intracanal medicament containing oregano essential oil. AIP Conf. Proc. 5 October 2020; 2274 (1): 050007. https://doi.org/10.1063/5.0022680
Download citation file:
Sign in
Don't already have an account? Register
Sign In
You could not be signed in. Please check your credentials and make sure you have an active account and try again.
Pay-Per-View Access
$40.00
Citing articles via
The effect of a balanced diet on improving the quality of life in malignant neoplasms
Yu. N. Melikova, A. S. Kuryndina, et al.
Animal intrusion detection system using Mask RCNN
C. Vijayakumaran, Dakshata, et al.
Recognition of cat ras of face and body using convolutional neural networks
Akhmad Wahyu Aji, Esmeralda Contessa Djamal, et al.
Related Content
Assessment of biocompatibility of cranberry and grape seed extract as an intracanal medicament
AIP Conf. Proc. (October 2020)
Assessment of antioxidant activity of an intracanal medicament containing grape seed extract
AIP Conf. Proc. (October 2020)
Antimicrobial activity of Bulgarian white oregano essential oils and ethanol extracts
AIP Conf. Proc. (December 2023)
Bacterial profile in skin ulcer infection with special resistance to antibiotics in AL-Sader hospital in Al-Najaf city
AIP Conference Proceedings (January 2022)
Role of isolated compounds from spices and herbs in natural medicinal care or therapy-A review
AIP Conf. Proc. (January 2024)