The study on implementation of flipped classroom cooperative learning in Analytical Chemistry Course at Diploma Program of Analytical Chemistry Islamic University of Indonesia was done. The study aims to explore the effect of the application of flipped classroom cooperative learning to the learning outcomes course in volumetric testing. Lecturers deliver video and learning material before face-to-face activities in class using the learning management system in Google classroom which is integrated with academic information systems. Students study learning material using smartphones, tablets, computers, or laptops. During face-to-face activities in class, students conduct cooperative learning discussion activities using the methods of student team achievement division (STAD) and team games tournament (TGT). Face-to-face activities in class are used for cooperative learning with the methods of student team achievement division (STAD) and team games tournament (TGT). Lecturers confirm student learning outcomes with interactive quiz and team games tournament followed by reflection on learning to get feedback on the process and results of learning outcomes. Data collection on measurement results of learning outcomes is done through assignment activities, quizzes, team games tournament, midterm, and final semester exams. Based on the results of the study showed that the application of inverted cooperative learning classes increased learning outcomes for volumetric topics in the analytical chemistry course. The t-test for two-sample assuming unequal variances results, obtained ttest (3.9653) > ttable (1.9845) which shows that the flipped classroom cooperative method can increase the average student learning outcomes compared to the cooperative learning method. The flipped classroom cooperative learning class method provides a significant increase in learning outcomes course of volumetric principles and the stoichiometric aspects of volumetric analysis. The flipped classroom cooperative learning method is able to improve the learning outcomes of analytical chemistry courses on volumetric principles and stoichiometric aspects with ttest of 10.7878 and 11.22232> ttable, respectively.

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