The use of mobile phones in Organic Chemistry course learning has been performed for Chemistry Education students. This study was a quantitative-descriptive research that collected data with students’ discussion in instant messenger LINE and students’ responses questionnaire. The result showed students having an interest in the discussion topic, having the opportunity to interact with lecturers longer, and increasing the frequency of reading articles related to organic chemicals with mobile phones. From the questionnaire, it can be concluded that students’ responses in this were good.

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