The synthesis and biological evaluation of prodrug amide derivatives based on phenylene dioxy di acetic acid

Seven unused amides compounds (1a-7a) prodrug subordinates based on phenylene di oxy di acidic acid as well as ponder their antibacterial and DPPH radicals rummaging exercises The structure of synthesized compounds were explained through cutting edge spectroscopic strategies counting NMR, IR and UV. (4a-7a) The antibaterial effect of compounds 1a-7a were estimated on Escherichia coli (-) and Staphylococcus aureus (+),compound 6 show the simplification effective, inhibitory viability with hindrance values of 28 and 20 µg/ml for Escherichia coli (-) and Staphylococcus aureus (+), respectively. Compounds shown DPPH radicals rummaging movement compare to the ascorbic corrosive. As a conclusion, seven compounds have been synthesized and the compounds appeared potential against two microscopic organisms species and DPPH radicals. The discoveries of this ponder can upgrade the understanding of natural exercises of the amide compounds.