Seven unused amides compounds (1a-7a) prodrug subordinates based on phenylene di oxy di acidic acid as well as ponder their antibacterial and DPPH radicals rummaging exercises The structure of synthesized compounds were explained through cutting edge spectroscopic strategies counting NMR, IR and UV. (4a-7a) The antibaterial effect of compounds 1a-7a were estimated on Escherichia coli (-) and Staphylococcus aureus (+),compound 6 show the simplification effective, inhibitory viability with hindrance values of 28 and 20 µg/ml for Escherichia coli (-) and Staphylococcus aureus (+), respectively. Compounds shown DPPH radicals rummaging movement compare to the ascorbic corrosive. As a conclusion, seven compounds have been synthesized and the compounds appeared potential against two microscopic organisms species and DPPH radicals. The discoveries of this ponder can upgrade the understanding of natural exercises of the amide compounds.
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25 March 2020
2ND INTERNATIONAL CONFERENCE ON MATERIALS ENGINEERING & SCIENCE (IConMEAS 2019)
25–29 September 2019
Baghdad, Iraq
Research Article|
March 25 2020
The synthesis and biological evaluation of prodrug amide derivatives based on phenylene dioxy di acetic acid
Jalal Hassan Mohammed;
Jalal Hassan Mohammed
a)
1
College of Pharmacy, University of Kerbala
, kerbala, Iraq
.a)Corresponding author: [email protected]
Search for other works by this author on:
Saadon Abdulla Aowda
Saadon Abdulla Aowda
2
Department of Chemistry, Faculty of Science, University Of Babylon
, Babylon, Iraq
.
Search for other works by this author on:
Jalal Hassan Mohammed
1,a)
Saadon Abdulla Aowda
2
1
College of Pharmacy, University of Kerbala
, kerbala, Iraq
.
2
Department of Chemistry, Faculty of Science, University Of Babylon
, Babylon, Iraq
.
a)Corresponding author: [email protected]
AIP Conf. Proc. 2213, 020157 (2020)
Citation
Jalal Hassan Mohammed, Saadon Abdulla Aowda; The synthesis and biological evaluation of prodrug amide derivatives based on phenylene dioxy di acetic acid. AIP Conf. Proc. 25 March 2020; 2213 (1): 020157. https://doi.org/10.1063/5.0000138
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