Purslane (Portulaca oleracea L.) contains high omega – 3. Therefore, it can be utilized as a health supplement. In this work, omega-3 was isolated by using extraction method. Maceration extraction was chosen because of the simple process and it could extract many simplicia in 1 time extraction. The use of alcohol and water mixture as a solvent with various amount of solvent and maceration time resulted in the omega-3 extract. The omega-3 extract can be used as a reference in determining the variation for the best amount of solvents in extraction of purslane with dried leaf simplicia. Based on the Gas Chormatography-Mass Spectroscopy analysis, it was revealed that the highest concentration of omega-3 was obtained by the 20 days maceration using 1 liter solvent, resulting in 19.894 g filtrate and omega-3 concentrations of 220 mg ω-3 / 100g dried leaf simplicia. This result was better than the extraction conducted using 3 liters of solvent with the extraction time of 30 days which resulted in the highest amount of extract of 36.56 g. The extract obtained was then encapsulated using the plate drying method which could maintain the quality of the core material. The quality was characterized with phase change to become solid after the encapsulation process so the core material can be safely consumed by humans.

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