Total body irradiation with volumetric modulated arc therapy (VMAT) is new and advanced method of dose delivery. In this paper EPIQAis used for the quality assurance of the machine specific and pre-treatment patient specific QA. EPIQAis a program which converts a dosimetric image acquired by an electronic portal imaging devices (EPID) into absorbed dose map and allows comparison of the dose map with reference dose distribution. The aim of the present study is to present the application of EPIQA to machine specific and pre-treatment RapidArc patient specific QAs.QAs were performed repeatedly to check the stability and reproducibility of LINAC performance. It also helps to ensure the accuracy and quality of the TBI delivery to the patients. For all the QAprocedures raw images were obtained by positioning EPID source to imager distance (SID) of 100 cm. The experimental results indicates that, a Quality Assurance program can reliably incorporate EPIQA as an instrument for LINAC QAs including both static as well as intensity modulated fields (IMRT, RapidArc).

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