Dental abscess which commonly founded in the community are periapical, pericoronal and periodontal abscesses. Abscesses are caused by various bacteria both Gram-positive and Gram-negative. Abscess treatment uses antibiotics. Antibiotics that usual used were broad spectrum of β lactam and 1st, 2nd, and 3rd generation of cephalosporin groups. The irrational use of antibiotics will impact resistance and multi-antibiotic resistance. Methicillin-Resistant Staphylococcus aureus (MRSA) and Extended-Spectrum Beta-lactamase (ESBL) is probably the best example of Multi-resistance bacteria. This research is aimed to identify bacteria and analyze the pattern of multi-resistant antibiotics in dental abscess patients at Arifin Achmad General Hospital of Riau Province. This study was carried out in laboratory of Microbiology, Faculty of Medicine, University of Riau. Samples from abscess were cultured and identified with MRSA and ESBL test conventionally. The results are analyzed and presented in frequency tables and expressed in percentage. There are 34 samples which consisted of periodontal abscess (55.9%) and periapical (44.1%). The highest number of Gram-positive bacteria was Streptococcus alpha hemolyticus (40.0%) and Coagulase negative Staphylococcus (CNS) (40.0%). While the highest number of Gram-negative bacteria was Escherichia coli (31.58%) and Pseudomonas sp (31.58%). There were no multiresistant MRSA bacteria, but 15.79% of ESBL was found from the presumptive test and the most were Escherichia coli (66.67%). From the confirmative test, we found Escherichia coli (33.33%).

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