The present of cadmium in the body is nephrotoxic due to it’s effect in increasing urea and creatinine. Tea mistletoe (Scurrula atropurpurea) has quercetin compound that able to become cadmium chelator. This study aims to know the effect and effective dose tea mistletoe as natural chelator in detoxifying cadmium towards urea and creatinine levels of male white rats (Rattus norvegicus). The study result obtained that all doses of tea mistletoe extract decreased urea and creatinine levels of rat that induced by cadmium. Effective dose of tea mistletoe extract that decreased urea and creatinine levels was 400 mg.kg−1 WB.

1.
F
Istarani
and
S
Ellina
J. Tek. Pomits
3
53
(
2014
).
2.
M
Rachmaningrum
,
W
Eka
, and
P
Kancitra
J. Rekayasa Lingkung.
3
1
(
2015
).
3.
M
Wallin
,
G
Sallsten
,
E
Fabricus-Lagging
,
C
Öhrn
,
T
Lundh
, and
L
Barregard
Environ. Heal.
12
1
(
2013
).
4.
H
Alatas
,
T
Taralan
,
P
Partini
, and
O
Sudung
Buku Ajar Nefrologi Anak
(
Jakarta
:
Balai Penerbit Fakultas Kedokteran Universitas Indonesia
.) (
2010
).
5.
R.
Nedecky
,
L
Nejdl
,
J
Gumulec
,
O
Zitka
,
M
Masarik
,
T
Eckschlager
,
M
Stiborova
,
V
Adam
, and
R
Kizek
Int. J. Mol. Sci.
14
6044
(
2013
).
6.
Y
Wetipo
,
C
Jubhar
, and
S
Ferdy
Produksi ROS Akibat Ion Logam Berat dan Mekanisme Penangkal dengan Antioksidan
(
Salatiga
:
Universitas Kristen Satya Wacana
) (
2013
).
7.
S
Astuti
J. Teknol. Ind. Dan Has. Pertan.
13
126
(
2008
).
8.
J
Zídková
,
M
Melčová
,
K
Bartošová
,
I
Šestáková
,
V
Zídek
,
J
Száková
,
D
Miholová
, and
P
Tlustoš
Czech J. Anim. Sci.
59
548
(
2014
).
9.
Hernayanti
,
S Slamet
, and
M
Alfi
J. LPPM Unsoed
7
615
(
2017
).
10.
J
Simanjuntak
Bina Widya
23
135
(
2012
).
11.
Fitrya
J. Penelit. Sains
14
33
(
2011
).
12.
J
Agung
,
P
Sri
, and
R
Isworo
J. Sains Dan Mat.
22
89
(
2014
).
13.
L
Anwar
,
A
John
, and
Herdini
Chempublish J.
1
13
(
2015
).
14.
G
Cirillo
and
I
Francesca
Antioxidant Polymers: Synthesis, Properties, and Applications
(
Italy
:
Scrivener Publishing LLC
) (
2012
).
15.
R
Herlambang
,
R
Dina
, and
F
Mia
Galen. J. Pharm.
1
59
(
2015
).
16.
DiaSys
 Diagnostic Reagent for Quantitative In Vitro Determination of Urea in Serum, Plasma or Urine on Photometric Systems (
Holzheim
:
DiaSys Diagnostic Systems GmbH
.) (
2015
).
17.
DiaSys
Diagnostic Reagent for Quantitative In Vitro Determination of Creatinine in Serum, Plasma or Urine on Photometric Systems
(
Holzheim
:
DiaSys Diagnostic Systems GmbH
.) (
2016
).
18.
M
Derelanko
Toxicologist’s Pocket Handbook
(
Morristown
:
CRC Press
) (
2000
).
19.
N
Amir
,
S
Eddy
,
Hardoko
, and
N
Happy
J. IPTEKS PSP
2
283
(
2015
).
20.
O
Olubunmi
,
S.
Olantuji
,
J.
Owolabi
,
A.
Fabiyi
, and
J.
Olanrewaju
Am. J. Clin. Exp. Med.
4
112
(
2016
).
21.
Martono
and
Satino
J. Ners
9
43
(
2014
).
22.
J
Sommar
,
M.
Svensson
,
B.
Björ
,
S.
Elmståhl
,
G
Hallmans
,
T
Lundh
,
S M.
Schön
,
S
Skerfving
, and
I.
Bergdah
Environ. Heal.
12
1
(
2013
).
23.
N
Bashir
,
V
Manoharan
, and
S
Prabu
STM Journals
4
1
(
2014
).
24.
T
Bu
,
M
Yuling
,
Z
Weidong
, and
Z
Caiqiao
Anat. Rec.
294
520
(
2011
).
25.
J
Priyanto
,
S
Pujiyanto
, and
I
Rukmi
J. Sains Dan Mat.
22
89
(
2014
).
26.
M
Symonowicz
and
M
Kolanek
Biotechnol. Food Sci.
76
35
(
2012
).
27.
Y
Sinseng
Uji Aktivitas Antioksidan dengan Metode Radikal DPPH (1,1-Difenil-2-Pikrilhidrazil) dan Penetapan Kadar Fenolik Total Fraksi Etil Asetat Ekstrak Etanol Daun Benalu Teh (Scurrula atropurpurea (Bl.) Dans) dari Pohon Kemiri (Aleurites moluccana (L.) Willd) Skripsi
(
Yogyakarta
:
Universitas Sanata Dharma
) n.d.
28.
D
Zahroh
,
A
Nour
, and
S
Hari
J. Ilm. Biosaintropis
3
8
(
2017
).
This content is only available via PDF.
You do not currently have access to this content.