A new class of mono and bis heterocycles- 4-(chloromethyl)-2-((arylethenesulfonyl) methyl)oxazoles and 4- ((2-((arylethenesulfonyl)methyl)oxazol-4-yl)methyl)morpholines/ thiomor- pholines were prepared from the synthetic intermediate arylethenesulfonylacetic acid adopting simple and well versed synthetic methodologies and were studied for their respective antimicrobial activity. The compounds 3c and 6c having chloro substituent on the aromatic ring showed greater antimicrobial activity than those with electron donating groups. All the entitled compounds were characterized by 1H, 13C NMR, mass spectra.

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