A variety of azolylindolylthiazolidinones and azetidinones were synthesized by the cyclocondensation of azolylindolyl schiff’s bases with mercaptoacetic acid and chloroacetyl chloride, respectively under ultrasonication. The methoxy substituted thiazolylindolylazetidinone (12) and imidazolylindolylazetidinone (13) were exhibited excellent antibacterial activity against B. subtilis. The compound 13 was also showed excellent antifungal activity against A. niger.
Synthesis, characterization and antimicrobial activity of azetidinone and thiazolidinone derivatives
P. Siva Sankar, K. Divya, G. Dinneswara Reddy, V. Padmavathi, Grigory V. Zyryanov; Synthesis, characterization and antimicrobial activity of azetidinone and thiazolidinone derivatives. AIP Conf. Proc. 11 January 2019; 2063 (1): 040047. https://doi.org/10.1063/1.5087379
Download citation file: