A variety of azolylindolylthiazolidinones and azetidinones were synthesized by the cyclocondensation of azolylindolyl schiff’s bases with mercaptoacetic acid and chloroacetyl chloride, respectively under ultrasonication. The methoxy substituted thiazolylindolylazetidinone (12) and imidazolylindolylazetidinone (13) were exhibited excellent antibacterial activity against B. subtilis. The compound 13 was also showed excellent antifungal activity against A. niger.

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