Bay leaf (Syzygium polyanthum (Wight) Walp) is not only can be used as food seasoning and flavoring but also as medicine. Indonesian National Agency of Drug and Food Control established bay leaf as one of the nine major medicinal plants. The aim of this study was to conduct in vitro bioactivities analysis as antidiabetic, antioxidant and toxicity of bay leaf water extract. Bay leaf used in this study was collected from the gardens of research center for science and technology (Puspiptek) Serpong, Tangerang Selatan Indonesia, dried and extracted steeping in boiled water. Antidiabetic was measured using α-glucosidase inhibition method; antioxidant was measured using DPPH free radical flushing activity method; toxicity test was measured using Brine Shrimp Lethality Test (BSLT). The resulst showed that the decoction of bay leaves showed antidiabetic (41.4% inhibition of a-glucosidase) and antioxidant (49.4% scavenging of DPPH) activities at sample concentration of 50 µg/ml and very low toxic effect on brine shrimp larvae (LD50> 1000µg / mL). The results suggest that bay leaf water extract has potential to be used in development of functional drink to reduce diabetic risk.
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7 November 2018
PROCEEDINGS OF THE 4TH INTERNATIONAL SYMPOSIUM ON APPLIED CHEMISTRY 2018
1–2 November 2018
Banten, Indonesia
Research Article|
November 07 2018
Bioactivities of Syzygium polyanthum (Wight) Walp leaf extract for decreasing diabetic risk
Indah Dwiatmi Dewijanti;
Indah Dwiatmi Dewijanti
*
1)
Research Center for Chemistry – Indonesian Institute of Sciences
, Kawasan PUSPIPTEK, Serpong, South Tangerang, Banten, Indonesia
*Corresponding author; e-mail: dewiruslan@yahoo.com
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Nina Artanti;
Nina Artanti
1)
Research Center for Chemistry – Indonesian Institute of Sciences
, Kawasan PUSPIPTEK, Serpong, South Tangerang, Banten, Indonesia
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Wibowo Mangunwardoyo;
Wibowo Mangunwardoyo
2)
Department of Biology, Faculty of Mathematic and Sciences, University of Indonesia
, Depok, 16424. Indonesia
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Muhammad Hanafi;
Muhammad Hanafi
1)
Research Center for Chemistry – Indonesian Institute of Sciences
, Kawasan PUSPIPTEK, Serpong, South Tangerang, Banten, Indonesia
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Jamilah Abbas;
Jamilah Abbas
1)
Research Center for Chemistry – Indonesian Institute of Sciences
, Kawasan PUSPIPTEK, Serpong, South Tangerang, Banten, Indonesia
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Megawati Megawati;
Megawati Megawati
1)
Research Center for Chemistry – Indonesian Institute of Sciences
, Kawasan PUSPIPTEK, Serpong, South Tangerang, Banten, Indonesia
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Minarti Minarti;
Minarti Minarti
1)
Research Center for Chemistry – Indonesian Institute of Sciences
, Kawasan PUSPIPTEK, Serpong, South Tangerang, Banten, Indonesia
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Dian Musdalifah;
Dian Musdalifah
1)
Research Center for Chemistry – Indonesian Institute of Sciences
, Kawasan PUSPIPTEK, Serpong, South Tangerang, Banten, Indonesia
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Lia Meilawati
Lia Meilawati
1)
Research Center for Chemistry – Indonesian Institute of Sciences
, Kawasan PUSPIPTEK, Serpong, South Tangerang, Banten, Indonesia
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*Corresponding author; e-mail: dewiruslan@yahoo.com
AIP Conf. Proc. 2024, 020011 (2018)
Citation
Indah Dwiatmi Dewijanti, Nina Artanti, Wibowo Mangunwardoyo, Muhammad Hanafi, Jamilah Abbas, Megawati Megawati, Minarti Minarti, Dian Musdalifah, Lia Meilawati; Bioactivities of Syzygium polyanthum (Wight) Walp leaf extract for decreasing diabetic risk. AIP Conf. Proc. 7 November 2018; 2024 (1): 020011. https://doi.org/10.1063/1.5064297
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