The research regarding the properties of thin films of hydroxyapatite doped with various ions such as zinc elaborated by spin-coating technique have rarely been fabricated and studies in recent years. In the present study Zn doped hydroxyapatite (ZnHAp) synthesized by a sol-gel method were coated on Ti substrates using a spin-coating technique. The thin films was characterized by Scanning Electron Microscopy (SEM) and Glow Discharge Optical Emission Spectroscopy (GDOES). The structural characterizations of ZnHAp thin films showed the presence of Zn and apatitic structure. The GD depth profiles revealed the successful embedding of the Zn ions in HAp structure. In addition, in vitro evaluation of the antifungal properties of ZnHAp demonstrated the potential antifungal effect of ZnHAp thin films against Staphylococcus aureus 0364 biofilm.

1.
Q.
Ding
,
X.
Zhang
and
Y.
Huang
,
J. Mater. Sci.
50
,
189
202
(
2015
).
2.
R.Y.
Zhang
,
S.
Cai
,
G.H.
Xu
,
H.
Zhao
,
Y.
Li
,
X.
Wang
,
K.
Huang
,
M.
Ren
and
X.
Wu
,
Appl. Surf. Sci.
313
,
896
904
(
2014
).
3.
Y.J.
Yan
,
Q.Q.
Ding
,
Y.
Huang
,
S.
Han
and
X.
Pang
,
Appl. Surf. Sci.
305
,
77
85
(
2014
).
4.
R.A.
Surmenev
,
M.A.
Surmeneva
and
A.A.
Ivanova
,
Acta Biomater
10
,
557
579
(
2014
).
5.
B.M.
Mihalcea
,
Phys. Scr.
2010
,
T140
(
2010
).
6.
M.H.
da Prado Silva
,
F.N.
Moura
,
D.
da Navarro Rocha
,
L.A.
Gobbo
,
A.M.
Costa
and
L.H.L.
Louro
,
Surf. Coat. Technol.
249
,
109
117
(
2014
).
7.
S.
Take
,
M.
Kato
,
T.
Asami
,
Y.
Aihara
,
S.
Izawa
and
T.
Atsumi
,
ECS Transactions
75
,
149
155
(
2017
).
8.
B.M.
Mihalcea
,
Phys. Scr.
2011
,
T143
(
2011
).
9.
D.
Predoi
,
M.V.
Predoi
,
S.L.
Iconaru
,
M.
Ech Cherif El Kettani
,
D.
Leduc
and
A. M.
Prodan
,
Materials
10
,
681
(
2017
).
10.
H.Y.
Chen
,
E.L.
Zhang
and
K.
Yang
Mater. Sci. Eng. C
34
,
201
206
(
2014
).
11.
D.
Predoi
,
S.L.
Iconaru
,
M.
Albu
,
C.C.
Petre
and
G.
Jiga
,
Polymer Eng. Sci.
57
,
537
545
(
2017
).
12.
S.
Sutha
,
G.
Karunakaran
and
V.
Rajendran
Ceram. Int.
39
,
5205
5212
(
2013
).
13.
D.
Gopi
,
S.
Ramya
,
D.
Rajeswari
,
P.
Karthikeyan
and
L.
Kavitha
,
Colloid. Surf. A
451
,
172
180
(
2014
).
14.
S.L.
Iconaru
,
A.M.
Prodan
,
N.
Buton
and
D.
Predoi
,
Molecules
22
,
604
(
2017
) doi:.
15.
C.S.
Ciobanu
,
S.L
Iconaru
,
I.
Pasuk
,
B.S.
Vasile
,
A.R.
Lupu
,
A.
Hermenean
,
A.
Dinischiotu
and
D.
Predoi
,
Mater. Sci. Eng. C
,
33
,
1395
1402
(
2013
).
16.
C.S.
Ciobanu
,
F.
Massuyeau
,
L.V.
Constantin
and
D.
Predoi
,
Nanoscale Res. Lett.
6
,
613
(
2011
).
17.
C.L.
Popa
,
C.M.
Bartha
,
M.
Albu
,
R.
Guegan
,
M.
Motelica-Heino
,
M.C.
Chifiriuc
,
C.
Bleotu
,
M.L.
Badea
,
S.
Antohe
,
Dig. J. Nanomater. Biostruct.
10
,
681
691
(
2015
).
18.
A.
Groza
,
C. S.
Ciobanu
,
C.L.
Popa
,
S. L.
Iconaru
,
P.
Chapon
,
C.
Luculescu
,
M.
Ganciu
and
D.
Predoi
,
Polymers
8
,
131
(
2016
) doi:.
19.
S.L.
Iconaru
,
E.
Andronescu
,
C.S.
Ciobanu
,
A.M.
Prodan
,
P.
Le Coustumer
and
D.
Predoi
,
Dig. J. Nanomater. Biostruct.
7
,
399
409
(
2012
).
20.
C.S.
Ciobanu
,
A.
Groza
,
S.L.
Iconaru
,
C.L.
Popa
,
P.
Chapon
,
M.C.
Chifiriuc
,
R.
Hristu
,
G.A.
Stanciu
,
C.C.
Negrila
,
R.V.
Ghita
,
M.
Ganciu
, and
D.
Predoi
,
BioMed Res. Int.
2015
,
1
3
(
2015
).
21.
S.L.
Iconaru
,
P.
Chapon
,
P.
Le Coustumer
and
D.
Predoi
,
Sci. World J.
2014
,
1
8
(
2014
).
22.
V.
Stanić
,
S.
Dimitrijević
,
J.
Antić-Stanković
,
M.
Mitrić
,
B.
Jokić
,
I. B.
Plećaš
,
S.
Raičević
,
Applied Surface Science
Volume
256
, Issue
20
, 1 August
2010
, Pages
6083
6089
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