Brain metastases are one of the factors complicating the treatment of a malignant tumor. Radiation therapy, especially radiosurgery, plays an important role in the modern treatment practice. During 2011-2016, 32 patients (from 29 to 67 years old) with multiple brain metastases underwent the treatment with SRS or SRT in our center. The number of secondary lesions varied from 2 to 11. Eight patients underwent microsurgery resection. Seven patients had recurrence after whole brain radiotherapy. Thirty patient underwent single fraction SRS and two patients with large metastases (bigger than 3 cm) underwent fractionated SRT. The treatment was done with dedicated linear accelerator stereotactic system Elekta Axesse (Elekta AB, Stockholm, Sweden). Different stereotactic fixation devices were used, namely, Leksell G frame, non-invasive HeadFIX frame, and reinforced thermoplastic mask (IMRT perforation). All treatments included a volumetric modulated arc therapy (VMAT) technique and of Inage Guided Radiation Therapy (IGRT) technique. All lesions were treated from a single isocenter, which allowed reducing the treatment time and overall dose to the patient’s body. All patients suffered the treatment satisfactorily. No adverse reactions or complications were met in any case during or right after the treatment. Different stereotactic fixation devices and modern treatment techniques allowed creating an optimal, safe and comfortable way for patient treatment. The treatment time was from 15 to 50 minutes. Patient position verification after or during the treatment demonstrated good accuracy for all fixation types and low level of intrafraction motion.
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28 September 2017
PHYSICS OF CANCER: INTERDISCIPLINARY PROBLEMS AND CLINICAL APPLICATIONS: Proceedings of the International Conference on Physics of Cancer: Interdisciplinary Problems and Clinical Applications (PC IPCA’17)
23–26 May 2017
Tomsk, Russia
Research Article|
September 28 2017
Multiple brain metastases irradiation with Eleka Axesse stereotactic system Available to Purchase
P. V. Filatov;
P. V. Filatov
a)
1
Centre of Oncology and Radiotherapy, Meshalkin Siberian Federal Biomedical Research Centre
, Novosibirsk, Russia
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E. S. Polovnikov;
E. S. Polovnikov
b)
1
Centre of Oncology and Radiotherapy, Meshalkin Siberian Federal Biomedical Research Centre
, Novosibirsk, Russia
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K. Yu. Orlov;
K. Yu. Orlov
c)
2
Centre of Neurosurgery, Meshalkin Siberian Federal Biomedical Research Centre
, Novosibirsk, Russia
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A. V. Krutko;
A. V. Krutko
d)
3
Ya.L. Tsivyan Novosibirsk Research Institute of Traumatology and Orthopaedics
, Novosibirsk, Russia
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I. A. Kirilova;
I. A. Kirilova
e)
3
Ya.L. Tsivyan Novosibirsk Research Institute of Traumatology and Orthopaedics
, Novosibirsk, Russia
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A. V. Moskalev;
A. V. Moskalev
f)
4
Biostatistics and Clinical Trials Center
, Novosibirsk, Russia
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E. V. Filatova;
E. V. Filatova
g)
1
Centre of Oncology and Radiotherapy, Meshalkin Siberian Federal Biomedical Research Centre
, Novosibirsk, Russia
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A. A. Zheravin
A. A. Zheravin
h)
1
Centre of Oncology and Radiotherapy, Meshalkin Siberian Federal Biomedical Research Centre
, Novosibirsk, Russia
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P. V. Filatov
1,a)
E. S. Polovnikov
1,b)
K. Yu. Orlov
2,c)
A. V. Krutko
3,d)
I. A. Kirilova
3,e)
A. V. Moskalev
4,f)
E. V. Filatova
1,g)
A. A. Zheravin
1,h)
1
Centre of Oncology and Radiotherapy, Meshalkin Siberian Federal Biomedical Research Centre
, Novosibirsk, Russia
2
Centre of Neurosurgery, Meshalkin Siberian Federal Biomedical Research Centre
, Novosibirsk, Russia
3
Ya.L. Tsivyan Novosibirsk Research Institute of Traumatology and Orthopaedics
, Novosibirsk, Russia
4
Biostatistics and Clinical Trials Center
, Novosibirsk, Russia
AIP Conf. Proc. 1882, 020018 (2017)
Citation
P. V. Filatov, E. S. Polovnikov, K. Yu. Orlov, A. V. Krutko, I. A. Kirilova, A. V. Moskalev, E. V. Filatova, A. A. Zheravin; Multiple brain metastases irradiation with Eleka Axesse stereotactic system. AIP Conf. Proc. 28 September 2017; 1882 (1): 020018. https://doi.org/10.1063/1.5001597
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