The antibiotic resistance of pathogenic microorganisms has become a worldwide concern to public health. To overcome the current resistance problem, new antimicrobial agents are extremely needed. The aim of the present study was to evaluate the antibacterial activity of Satureja hortensis essential oils against seven clinical pathogens. Chemical compositions of hydro distillated essential oils from S. hortensis were analyzed by GS-MS. The antibacterial activity was investigated against Corynebacterium diphtheria, Salmonella typhimurium, Serratia plymuthica Yersinia enterocolitica, Y. frederiksenii, Y. pseudotuberculosis and Vibrio cholerae by the use of disc diffusion method and broth micro dilution method. The minimum inhibitory concentration (MIC) values of essential oils were found as low as 7.81 µg/mL. Notably, essential oils of S. hortensis exhibited remarkable antimicrobial activities against the tested clinical pathogens. The results indicate that these essential oils can be used in treatment of different infectious diseases.

Topics
Educational assessment, Antimicrobial agents, Microorganisms, Antibiotics, Pathogens
1.
R. S.
 
Herati
 and
E. E.
 
Blumberg
,
Curr. Opin. Infect. Dis.
 
25
(
4
),
445
–
449
(
2012
).
https://doi.org/10.1097/QCO.0b013e328354f192
Google Scholar
Crossref
Search ADS
PubMed
 
2.
R.
 
Hamoud
,
F.
 
Sporer
,
J.
 
Reichling
 and
M.
 
Wink
,
Phytomedicine
,
19
,
969
–
976
(
2012
).
https://doi.org/10.1016/j.phymed.2012.05.014
Google Scholar
Crossref
Search ADS
PubMed
 
3.
H. S. A. A.
 
Mohamed
,
W. S.
 
Abdelgadir
 and
A. Z. I.
 
Almagboul
,
Int. J. Adv. Res.
 
3
,
359
–
367
(
2015
).
Google Scholar
 
4.
A.
 
Fabio
,
C.
 
Cermelli
,
G.
 
Fabio
,
P.
 
Nicoetti
 and
P.
 
Quaglio
,
J. Phytother. Res.
 
21
,
374
–
377
(
2007
).
https://doi.org/10.1002/ptr.1968
Google Scholar
Crossref
Search ADS
 
5.
E.
 
Jeyakumar
 and
R.
 
Lawrence
,
T.
 
Pa
,
Asia. Pac. J. Trop. Biomed.
 
1
,
253
–
257
(
2011
).
https://doi.org/10.1016/S2221-1691(11)60165-2
Google Scholar
Crossref
Search ADS
 
6.
F.
 
Bakkali
,
S.
 
Averbeck
,
D.
 
Averbeck
 and
M.
 
Idaomar
,
Food Chem. Toxicol.
 
46
,
446
–
475
(
2008
).
https://doi.org/10.1016/j.fct.2007.09.106
Google Scholar
Crossref
Search ADS
PubMed
 
7.
M.
 
Hajji
,
O.
 
Masmoudi
,
N.
 
Souissi
,
Y.
 
Triki
,
S.
 
Kammoun
 and
M.
 
Nasri
,
Food Chem.
 
121
,
724
–
731
(
2010
).
https://doi.org/10.1016/j.foodchem.2010.01.021
Google Scholar
Crossref
Search ADS
 
8.
F.
 
Sahin
,
I.
 
Karaman
,
M.
 
Gulluce
,
H.
 
Ogutcu
,
M.
 
Sengul
,
A.
 
Adiguzel
, et al.,
J. Ethnopharmacol.
 
87
,
61
–
65
(
2003
)
https://doi.org/10.1016/S0378-8741(03)00110-7
Google Scholar
Crossref
Search ADS
PubMed
 
9.
V.
 
Hajhashemi
,
H.
 
Sadraei
,
A. R.
 
Ghannadi
 and
M.
 
Mohseni
,
J. Ethnopharmacol.
 
71
,
187
–
192
(
2000
).
https://doi.org/10.1016/S0378-8741(99)00209-3
Google Scholar
Crossref
Search ADS
PubMed
 
10.
H. J. D.
 
Dorman
 and
R.
 
Hiltunen
,
Food Chem.
 
88
(
2
),
193
–
199
(
2003
).
https://doi.org/10.1016/j.foodchem.2003.12.039
Google Scholar
Crossref
Search ADS
 
11.
N.
 
Boyraz
 and
M.
 
Ozcan
,
Int. J. Food. Microbiol.
 
107
,
238
–
242
(
2006
).
https://doi.org/10.1016/j.ijfoodmicro.2005.10.002
Google Scholar
Crossref
Search ADS
PubMed
 
12.
I.
 
Miller
 and
T.
 
Berger
,
Bacteria identification by gas chromatographyof whole cell fatty acids
.
Hewlett-Packard Gas Chromatography Application Note Hewlett-Packard Co Alto CA
 
228
–
238
(
1985
).
Google Scholar
 
13.
P. R.
 
Murray
,
E. J.
 
Baron
,
M. A.
 
Pfaller
,
F. C.
 
Tenover
 and
R. H.
 
Yolke
,
Manual of Clinical Microbiology
(eds)
American Society for Microbiology
,
Washington, DC
,
1482
(
1995
).
Google Scholar
 
14.
J. R.
 
Zgoda
 and
J. R.
 
Porter
,
Pharm. Biol.
 
39
,
221
–
225
(
2001
).
https://doi.org/10.1076/phbi.39.3.221.5934
Google Scholar
Crossref
Search ADS
 
15.
A.
 
Gormez
,
S.
 
Bozari
,
D.
 
Yanmis
,
M.
 
Gulluce
,
F.
 
Sahin
,
G.
 
Agar
,
Polish Journal of Microbiology
,
64
(
2
):
121
–
127
(
2015
).
Google Scholar
Crossref
Search ADS
PubMed
 
16.
J.
 
Gora
,
A.
 
Lis
 and
A. L.
 
Ewandowski
,
J. Essent. Oil. Res.
 
8
,
427
–
428
(
1996
).
https://doi.org/10.1080/10412905.1996.9700656
Google Scholar
Crossref
Search ADS
 
17.
K. P.
 
Svoboda
,
Int. J. Aromath.
 
13
,
196
–
202
(
2003
).
https://doi.org/10.1016/S0962-4562(03)00038-9
Google Scholar
Crossref
Search ADS
 
18.
F.
 
Sefidkon
,
K.
 
Abbasi
 and
G.
 
Bakhshi
,
Food Chem.
 
99
,
19
–
23
(
2006
).
https://doi.org/10.1016/j.foodchem.2005.07.026
Google Scholar
Crossref
Search ADS
 
19.
J.
 
Hadiana
,
S. N.
 
Ebrahimi
 and
P.
 
Salehic
,
Ind. Crop. Prod.
 
32
,
62
–
69
(
2010
).
https://doi.org/10.1016/j.indcrop.2010.03.006
Google Scholar
Crossref
Search ADS
 
20.
M.
 
Khajeh
,
J. Supercrit, Fluid
 
55
,
944
–
948
(
2011
).
https://doi.org/10.1016/j.supflu.2010.10.017
Google Scholar
Crossref
Search ADS
 
21.
M.
 
Gulluce
,
M.
 
Sokmen
,
D.
 
Daferera
,
G.
 
Agar
,
H.
 
Ozkan
,
N.
 
Kartal
,
M.
 
Polissiou
,
A.
 
Sokmen
 and
F.
 
Sahin
,
J. Agric. Food Chem.
 
51
:
3958
–
3965
(
2003
).
https://doi.org/10.1021/jf0340308
Google Scholar
Crossref
Search ADS
PubMed
 
22.
S.
 
Kizil
 and
F.
 
Uyar
,
Asian J. Chem.
 
18
,
1455
–
1461
(
2006
).
Google Scholar
 
23.
R.
 
Kotan
,
F.
 
Dadasoglu
,
S.
 
Kordali
,
A.
 
Cakır
,
N.
 
Dikbas
 and
R.
 
Cakmakcı
,
J. Agric. Techno.
 
3
,
299
–
306
(
2007
).
Google Scholar
 
24.
T.
 
Mihajilov-Krstev
,
D.
 
Radnovic
,
D.
 
Kitic
,
Z.
 
Stojanovic-Radic
 and
B.
 
Zlatkovic
.
Biotechnol. and Biotechnol. Eq.
 
23
:
1492
–
1496
. (
2009
).
https://doi.org/10.2478/V10133-009-0018-2
Google Scholar
Crossref
Search ADS
 
25.
R.
 
Kotan
,
A.
 
Cakir
,
F.
 
Dadasoglu
,
T.
 
Aydin
,
R.
 
Cakmakci
,
H.
 
Ozer
,
S.
 
Kordali
,
E.
 
Mete
 and
N.
 
Dikbas
,
J. Sci. Food Agr.
 
90
,
145
–
160
(
2010
).
https://doi.org/10.1002/jsfa.3799
Google Scholar
Crossref
Search ADS
 
This content is only available via PDF.
© 2017 Author(s).
2017
Author(s)
You do not currently have access to this content.