Science education standards for grammar schools (ISCED 3) urge more emphasis on students’ investigations in order to develop understanding but also scientific process skills (inquiry skills). It is true for not only science, but also mathematics and informatics. This approach is promoted to increase scientific literacy and inquiry skills development, however, there has not been many studies carried out in Slovakia to show the effect on students’ achievements. In cooperation with Institutes of mathematics and informatics there was a research designed in order to study the effect of synergetic implementation of inquiry activities across the three subjects of physics, mathematics and informatics. The effect was identified with the help of inquiry skills’ test and results were compared to those achieved by students subjected to more traditional teaching. In the contribution there are results of the study analyzed and discussed in details.

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