The study was conducted to determine the anti-hyperglycemic property in terms of α-glucosidase inhibitory activity of the various parts (corm, leaf and petiole) of Colocasia esculenta (L.) Schott var. PSB-VG #9. Each of the plant parts were extracted with 95% ethanol and concentrated using a rotary evaporator at 40 °C. The crude extracts were screened for the presence of alkaloids, flavonoids, glycosides and saponins using Thin Layer Chromatography. The α-glucosidase inhibitory activity of the crude extracts (50 mg/L) were assayed spectrophotometrically using a microplate reader. The results of the phytochemical screening revealed the presence of alkaloids, flavonoids, and saponins in the leaf part while flavonoids and saponins were detected in the petiole and only saponins were present in the corm. The assay showed that the percentage α-glucosidase inhibition of the 50 mg/L ethanolic crude extract of the corm, leaves and petiole of C. esculenta are 68.03, 71.64 and 71.39%, respectively. Statistical analysis shows significant differences in the α-glucosidase inhibition among the various plant parts. It can be concluded that the ethanolic crude extracts of the different parts of C. esculenta (L.) Schott var. PSB-VG #9 exhibited inhibitory activity against α-glucosidase and the presence of phytochemicals like alkaloids, flavonoids and saponins may have contributed greatly to the inhibitory activity of the plant extract and can be further subjected for isolation of the therapeutically active compounds with antidiabetes potency.
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12 January 2017
INTERNATIONAL SYMPOSIUM ON APPLIED CHEMISTRY (ISAC) 2016
3–5 October 2016
Tangerang Banten, Indonesia
Research Article|
January 12 2017
Preliminary phytochemical screening and alpha-glucosidase inhibitory activity of Philippine taro (Colocasia esculenta (L.) Schott var. PSB-VG #9)
Richemae Grace R. Lebosada;
Richemae Grace R. Lebosada
1Chemistry Department,
Central Mindanao University
, University Town, Musuan, Maramag, Bukidnon, 8714, Philippines
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Ivy L. Librando
Ivy L. Librando
a)
1Chemistry Department,
Central Mindanao University
, University Town, Musuan, Maramag, Bukidnon, 8714, Philippines
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a)
Corresponding author: [email protected]
AIP Conf. Proc. 1803, 020030 (2017)
Citation
Richemae Grace R. Lebosada, Ivy L. Librando; Preliminary phytochemical screening and alpha-glucosidase inhibitory activity of Philippine taro (Colocasia esculenta (L.) Schott var. PSB-VG #9). AIP Conf. Proc. 12 January 2017; 1803 (1): 020030. https://doi.org/10.1063/1.4973157
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